Detalhe da pesquisa
1.
Adenosine A2A receptor agonists and PDE inhibitors: a synergistic multitarget mechanism discovered through systematic combination screening in B-cell malignancies.
Blood;
116(4): 593-602, 2010 Jul 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20382846
2.
Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication.
Mol Syst Biol;
6: 375, 2010 Jun 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20531405
3.
Chemical combination effects predict connectivity in biological systems.
Mol Syst Biol;
3: 80, 2007.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17332758
4.
Multicomponent therapeutics for networked systems.
Nat Rev Drug Discov;
4(1): 71-8, 2005 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15688074
5.
Adenosine A2A and beta-2 adrenergic receptor agonists: novel selective and synergistic multiple myeloma targets discovered through systematic combination screening.
Mol Cancer Ther;
11(7): 1432-42, 2012 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22474168
6.
Therapeutic selectivity and the multi-node drug target.
Discov Med;
8(43): 185-90, 2009 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20040268
7.
Selective amplification of glucocorticoid anti-inflammatory activity through synergistic multi-target action of a combination drug.
Arthritis Res Ther;
11(1): R12, 2009.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19171052
8.
Synergistic drug combinations tend to improve therapeutically relevant selectivity.
Nat Biotechnol;
27(7): 659-66, 2009 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19581876
9.
The novel combination of chlorpromazine and pentamidine exerts synergistic antiproliferative effects through dual mitotic action.
Cancer Res;
67(23): 11359-67, 2007 Dec 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18056463
10.
Systematic discovery of multicomponent therapeutics.
Proc Natl Acad Sci U S A;
100(13): 7977-82, 2003 Jun 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12799470