Detalhe da pesquisa
1.
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
Alzheimers Dement;
19(4): 1245-1259, 2023 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35993441
2.
HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS.
Acta Neuropathol;
144(3): 465-488, 2022 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35895140
3.
C9orf72 loss-of-function: a trivial, stand-alone or additive mechanism in C9 ALS/FTD?
Acta Neuropathol;
140(5): 625-643, 2020 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32876811
4.
TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish.
Front Cell Neurosci;
18: 1340240, 2024.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38463699
5.
Antisense, but not sense, repeat expanded RNAs activate PKR/eIF2α-dependent ISR in C9ORF72 FTD/ALS.
Elife;
122023 04 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37073950
6.
Exploring the alternative: Fish, flies and worms as preclinical models for ALS.
Neurosci Lett;
759: 136041, 2021 08 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34118308