Detalhe da pesquisa
1.
Inflammatory Endotype-associated Airway Microbiome in Chronic Obstructive Pulmonary Disease Clinical Stability and Exacerbations: A Multicohort Longitudinal Analysis.
Am J Respir Crit Care Med;
203(12): 1488-1502, 2021 06 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33332995
2.
Microbiome recovery in adult females with uncomplicated urinary tract infections in a randomised phase 2A trial of the novel antibiotic gepotidacin (GSK140944).
BMC Microbiol;
21(1): 181, 2021 06 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34130619
3.
In Vitro Activity and Microbiological Efficacy of Gepotidacin from a Phase 2, Randomized, Multicenter, Dose-Ranging Study in Patients with Acute Bacterial Skin and Skin Structure Infections.
Antimicrob Agents Chemother;
64(3)2020 02 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31818823
4.
The sputum microbiome is distinct between COPD and health, independent of smoking history.
Respir Res;
21(1): 183, 2020 Jul 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32664956
5.
The Microbiome Factor in Drug Discovery and Development.
Chem Res Toxicol;
33(1): 119-124, 2020 01 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31802667
6.
Airway host-microbiome interactions in chronic obstructive pulmonary disease.
Respir Res;
20(1): 113, 2019 Jun 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31170986
7.
Sputum microbiome temporal variability and dysbiosis in chronic obstructive pulmonary disease exacerbations: an analysis of the COPDMAP study.
Thorax;
73(4): 331-338, 2018 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29269441
8.
Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations.
Thorax;
73(5): 422-430, 2018 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29386298
9.
Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response.
J Virol;
90(9): 4807-4826, 2016 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26937035
10.
SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1.
J Virol;
90(13): 5939-5952, 2016 07 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27099310
11.
Orthogonal intercellular signaling for programmed spatial behavior.
Mol Syst Biol;
12(1): 849, 2016 Jan 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26814193
12.
Lung microbiome dynamics in COPD exacerbations.
Eur Respir J;
47(4): 1082-92, 2016 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26917613
13.
Correction to: Microbiome recovery in adult females with uncomplicated urinary tract infections in a randomised phase 2A trial of the novel antibiotic gepotidacin (GSK2140944).
BMC Microbiol;
21(1): 293, 2021 Oct 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34702186
14.
Thousands of chemical starting points for antimalarial lead identification.
Nature;
465(7296): 305-10, 2010 May 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20485427
15.
Microbiome changes in healthy volunteers treated with GSK1322322, a novel antibiotic targeting bacterial peptide deformylase.
Antimicrob Agents Chemother;
59(2): 1182-92, 2015 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25487798
16.
Bacterial resistance to leucyl-tRNA synthetase inhibitor GSK2251052 develops during treatment of complicated urinary tract infections.
Antimicrob Agents Chemother;
59(1): 289-98, 2015 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25348524
17.
Data mining the human gut microbiota for therapeutic targets.
Brief Bioinform;
13(6): 751-68, 2012 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22445903
18.
Target prediction for an open access set of compounds active against Mycobacterium tuberculosis.
PLoS Comput Biol;
9(10): e1003253, 2013.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24098102
19.
Fructose controlled ionophoric activity of a cholate-boronic acid.
Org Biomol Chem;
12(16): 2576-83, 2014 Apr 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24615337
20.
Connection to mental health care upon community reentry for detained youth: a qualitative study.
BMC Public Health;
14: 117, 2014 Feb 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24499325