Detalhe da pesquisa
1.
Intrathecal Gene Therapy for Giant Axonal Neuropathy.
N Engl J Med;
390(12): 1092-1104, 2024 03 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38507752
2.
Prednisolone and rapamycin reduce the plasma cell gene signature and may improve AAV gene therapy in cynomolgus macaques.
Gene Ther;
31(3-4): 128-143, 2024 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37833563
3.
Adenovirus-Antibody Complexes Contributed to Lethal Systemic Inflammation in a Gene Therapy Trial.
Mol Ther;
28(3): 784-793, 2020 03 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32035027
4.
Class I-restricted T-cell responses to a polymorphic peptide in a gene therapy clinical trial for α-1-antitrypsin deficiency.
Proc Natl Acad Sci U S A;
114(7): 1655-1659, 2017 02 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28137880
5.
5 Year Expression and Neutrophil Defect Repair after Gene Therapy in Alpha-1 Antitrypsin Deficiency.
Mol Ther;
25(6): 1387-1394, 2017 06 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28408179
6.
Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII.
Mol Ther;
24(2): 206-216, 2016 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26447927
7.
Results at 2 Years after Gene Therapy for RPE65-Deficient Leber Congenital Amaurosis and Severe Early-Childhood-Onset Retinal Dystrophy.
Ophthalmology;
123(7): 1606-20, 2016 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27102010
8.
Comparative Study of Liver Gene Transfer With AAV Vectors Based on Natural and Engineered AAV Capsids.
Mol Ther;
23(12): 1877-87, 2015 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26412589
9.
Increased mucosal CD4+ T cell activation in rhesus macaques following vaccination with an adenoviral vector.
J Virol;
88(15): 8468-78, 2014 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24829340
10.
Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid.
Nat Med;
12(8): 967-71, 2006 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16845388
11.
AAV8-mediated hepatic gene transfer in infant rhesus monkeys (Macaca mulatta).
Mol Ther;
19(11): 2012-20, 2011 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21811248
12.
Preclinical safety evaluation of AAV2-sFLT01- a gene therapy for age-related macular degeneration.
Mol Ther;
19(2): 326-34, 2011 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21119620
13.
Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy.
Proc Natl Acad Sci U S A;
106(38): 16363-8, 2009 Sep 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19706466
14.
Creation of a panel of vectors based on ape adenovirus isolates.
J Gene Med;
13(1): 17-25, 2011 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21259405
15.
Isolation and characterization of adenoviruses persistently shed from the gastrointestinal tract of non-human primates.
PLoS Pathog;
5(7): e1000503, 2009 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19578438
16.
The pleiotropic effects of natural AAV infections on liver-directed gene transfer in macaques.
Mol Ther;
18(1): 126-34, 2010 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19888196
17.
Systematic evaluation of AAV vectors for liver directed gene transfer in murine models.
Mol Ther;
18(1): 118-25, 2010 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19861950
18.
Host immune responses to chronic adenovirus infections in human and nonhuman primates.
J Virol;
83(6): 2623-31, 2009 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19116257
19.
A new genetic vaccine platform based on an adeno-associated virus isolated from a rhesus macaque.
J Virol;
83(24): 12738-50, 2009 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19812149
20.
Isolating Human Monoclonal Antibodies Against Adeno-Associated Virus From Donors With Pre-existing Immunity.
Front Immunol;
11: 1135, 2020.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32733434