Detalhe da pesquisa
1.
Biallelic Variants of MRPS36 Cause a New Form of Leigh Syndrome.
Mov Disord;
2024 Apr 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38685873
2.
A Recurrent Gain-of-Function Mutation in CLCN6, Encoding the ClC-6 Cl-/H+-Exchanger, Causes Early-Onset Neurodegeneration.
Am J Hum Genet;
107(6): 1062-1077, 2020 12 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33217309
3.
Mutations in KCNK4 that Affect Gating Cause a Recognizable Neurodevelopmental Syndrome.
Am J Hum Genet;
103(4): 621-630, 2018 10 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30290154
4.
Pathogenic PTPN11 variants involving the poly-glutamine Gln255 -Gln256 -Gln257 stretch highlight the relevance of helix B in SHP2's functional regulation.
Hum Mutat;
41(6): 1171-1182, 2020 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32112654
5.
Structural Determinants of Phosphopeptide Binding to the N-Terminal Src Homology 2 Domain of the SHP2 Phosphatase.
J Chem Inf Model;
60(6): 3157-3171, 2020 06 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32395997
6.
Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide.
Bioconjug Chem;
30(7): 1998-2010, 2019 07 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31145591
7.
Targeting the Pentose Phosphate Pathway: Characterization of a New 6PGL Inhibitor.
Biophys J;
115(11): 2114-2126, 2018 12 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30467026
8.
Molecular and cellular evidence of a direct interaction between the TRAF2 C-terminal domain and ganglioside GM1.
Int J Biochem Cell Biol;
167: 106508, 2024 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38142771
9.
Computational Evaluation of Peptide-Protein Binding Affinities: Application of Potential of Mean Force Calculations to SH2 Domains.
Methods Mol Biol;
2705: 113-133, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37668972
10.
Fluorescence Anisotropy and Polarization in the Characterization of Biomolecular Association Processes and Their Application to Study SH2 Domain Binding Affinity.
Methods Mol Biol;
2705: 93-112, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37668971
11.
Isoamphipathic antibacterial molecules regulating activity and toxicity through positional isomerism.
Chem Sci;
14(18): 4845-4856, 2023 May 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37181778
12.
Insights into internal dynamics of 6-phosphogluconolactonase from Trypanosoma brucei studied by nuclear magnetic resonance and molecular dynamics.
Proteins;
80(4): 1196-210, 2012 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22275079
13.
ScrewFit: combining localization and description of protein secondary structure.
Acta Crystallogr D Biol Crystallogr;
68(Pt 12): 1690-3, 2012 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23151634
14.
Communication: a minimal model for the diffusion-relaxation backbone dynamics of proteins.
J Chem Phys;
136(19): 191101, 2012 May 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22612073
15.
Least constraint approach to the extraction of internal motions from molecular dynamics trajectories of flexible macromolecules.
J Chem Phys;
135(8): 084110, 2011 Aug 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21895162
16.
Discriminating between competing models for the allosteric regulation of oncogenic phosphatase SHP2 by characterizing its active state.
Comput Struct Biotechnol J;
19: 6125-6139, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34900129
17.
Targeting Oncogenic Src Homology 2 Domain-Containing Phosphatase 2 (SHP2) by Inhibiting Its Protein-Protein Interactions.
J Med Chem;
64(21): 15973-15990, 2021 11 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34714648
18.
Molecular Investigation of SARS-CoV-2 Proteins and Their Interactions with Antiviral Drugs.
Viruses;
12(4)2020 04 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32295237
19.
Role of proteolytic enzymes in the COVID-19 infection and promising therapeutic approaches.
Biochem Pharmacol;
182: 114225, 2020 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32956643
20.
Expression of the PsMTA1 gene in white poplar engineered with the MAT system is associated with heavy metal tolerance and protection against 8-hydroxy-2'-deoxyguanosine mediated-DNA damage.
Plant Cell Rep;
28(8): 1179-92, 2009 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19506883