Detalhe da pesquisa
1.
Novel [1,3,4]Thiadiazole[3,2-a]pyrimidin-5-ones as Promising Biofilm Dispersal Agents against Relevant Gram-Positive and Gram-Negative Pathogens.
Mar Drugs;
22(3)2024 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38535474
2.
PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer.
Mol Cancer;
22(1): 138, 2023 08 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37596643
3.
1,3,4-Oxadiazole and 1,3,4-Thiadiazole Nortopsentin Derivatives against Pancreatic Ductal Adenocarcinoma: Synthesis, Cytotoxic Activity, and Inhibition of CDK1.
Mar Drugs;
21(7)2023 Jul 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37504943
4.
Structural Manipulations of Marine Natural Products Inspire a New Library of 3-Amino-1,2,4-Triazine PDK Inhibitors Endowed with Antitumor Activity in Pancreatic Ductal Adenocarcinoma.
Mar Drugs;
21(5)2023 May 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37233482
5.
Recent Developments in the Inhibition of Bacterial Adhesion as Promising Anti-Virulence Strategy.
Int J Mol Sci;
24(5)2023 Mar 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36902301
6.
Discovery of the 3-Amino-1,2,4-triazine-Based Library as Selective PDK1 Inhibitors with Therapeutic Potential in Highly Aggressive Pancreatic Ductal Adenocarcinoma.
Int J Mol Sci;
24(4)2023 Feb 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36835086
7.
Nortopsentins as Leads from Marine Organisms for Anticancer and Anti-Inflammatory Agent Development.
Molecules;
28(18)2023 Sep 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37764226
8.
Nanoparticle-Imprinted Silica Gel for the Size-Selective Capture of Silver Ultrafine Nanoparticles from Water.
Molecules;
28(10)2023 May 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37241766
9.
GSK3ß as a novel promising target to overcome chemoresistance in pancreatic cancer.
Drug Resist Updat;
58: 100779, 2021 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34461526
10.
Synthesis and Antioxidative Properties of 1,2,3,4-Tetrahydropyridine Derivatives with Different Substituents in 4-Position.
Molecules;
27(21)2022 Nov 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36364252
11.
A New Oxadiazole-Based Topsentin Derivative Modulates Cyclin-Dependent Kinase 1 Expression and Exerts Cytotoxic Effects on Pancreatic Cancer Cells.
Molecules;
27(1)2021 Dec 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35011251
12.
Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation.
Molecules;
26(1)2020 Dec 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33375417
13.
3-(6-Phenylimidazo [2,1-b][1,3,4]thiadiazol-2-yl)-1H-Indole Derivatives as New Anticancer Agents in the Treatment of Pancreatic Ductal Adenocarcinoma.
Molecules;
25(2)2020 Jan 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31947550
14.
Exploring the therapeutic potential of focal adhesion kinase inhibition in overcoming chemoresistance in pancreatic ductal adenocarcinoma.
Future Med Chem;
16(3): 271-289, 2024 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38269431
15.
[Hamman's syndrome in SARS-CoV-2 pneumonia]. / Síndrome de Hamman en neumonía por SARS-CoV-2.
Medicina (B Aires);
83(3): 475-478, 2023.
Artigo
em Espanhol
| MEDLINE
| ID: mdl-37379547
16.
1,2,4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation.
Eur J Med Chem;
249: 115134, 2023 Mar 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36709650
17.
HIV-1-induced nuclear invaginations mediated by VAP-A, ORP3, and Rab7 complex explain infection of activated T cells.
Nat Commun;
14(1): 4588, 2023 08 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37563144
18.
A Combination of Polymethoxyflavones from Citrus sinensis and Prenylflavonoids from Humulus lupulus Counteracts IL-1ß-Induced Differentiated Caco-2 Cells Dysfunction via a Modulation of NF-κB/Nrf2 Activation.
Antioxidants (Basel);
12(8)2023 Aug 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37627616
19.
Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification.
Eur J Med Chem;
234: 114233, 2022 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35286926
20.
Therapeutic Strategies To Counteract Antibiotic Resistance in MRSA Biofilm-Associated Infections.
ChemMedChem;
16(1): 65-80, 2021 01 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33090669