Detalhe da pesquisa
1.
Tyrosine kinase receptor B attenuates liver fibrosis by inhibiting TGF-ß/SMAD signaling.
Hepatology;
78(5): 1433-1447, 2023 11 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36800849
2.
In Vitro and In Vivo Antibacterial Activities of a Novel Quinolone Compound, OPS-2071, against Clostridioides difficile.
Antimicrob Agents Chemother;
65(4)2021 03 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33495229
3.
Correction for Oka et al., "In Vitro and In Vivo Antibacterial Activities of a Novel Quinolone Compound, OPS-2071, against Clostridioides difficile".
Antimicrob Agents Chemother;
66(3): e0233821, 2022 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35289646
4.
Combination of virtual screening and high throughput gene profiling for identification of novel liver X receptor modulators.
J Med Chem;
51(7): 2057-61, 2008 Apr 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18324758
5.
Discovery of potent and orally available malonyl-CoA decarboxylase inhibitors as cardioprotective agents.
J Med Chem;
49(14): 4055-8, 2006 Jul 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16821767
6.
Synthesis and structure-activity relationship of small-molecule malonyl coenzyme A decarboxylase inhibitors.
J Med Chem;
49(5): 1517-25, 2006 Mar 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16509570
7.
Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation.
Circ Res;
94(9): e78-84, 2004 May 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15105298
8.
Two-dimensional turbulent flow chromatography coupled on-line to liquid chromatography-mass spectrometry for solution-based ligand screening against multiple proteins.
J Chromatogr A;
1216(12): 2394-403, 2009 Mar 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19203758
9.
10.
Novel trifluoroacetophenone derivatives as malonyl-CoA decarboxylase inhibitors.
Bioorg Med Chem Lett;
17(4): 1127-30, 2007 Feb 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17234415
11.
Hamigerols A and B, unprecedented polysulfate sterol dimers from the Mediterranean sponge Hamigera hamigera.
J Nat Prod;
70(7): 1195-9, 2007 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17580909
12.
Myriaporones 1-4, cytotoxic metabolites from the Mediterranean bryozoan Myriapora truncata.
J Nat Prod;
70(3): 332-6, 2007 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17284072
13.
2-Aryl-N-acyl indole derivatives as liver X receptor (LXR) agonists.
Bioorg Med Chem Lett;
17(16): 4442-6, 2007 Aug 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17587573
14.
Synthesis and structure-activity relationship of 4-(2-aryl-cyclopropylamino)-quinoline-3-carbonitriles as EGFR tyrosine kinase inhibitors.
Bioorg Med Chem Lett;
17(21): 5978-82, 2007 Nov 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17827009
15.
Discovery and structure-activity relationship studies of indole derivatives as liver X receptor (LXR) agonists.
Bioorg Med Chem Lett;
17(12): 3473-9, 2007 Jun 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17416521
16.
Design and synthesis of heterocyclic malonyl-CoA decarboxylase inhibitors.
Bioorg Med Chem Lett;
16(3): 695-700, 2006 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16257202
17.
Heteroaryl substituted bis-trifluoromethyl carbinols as malonyl-CoA decarboxylase inhibitors.
Bioorg Med Chem Lett;
16(13): 3484-8, 2006 Jul 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16644218
18.
The medicinal chemistry of new agents to treat diabetes and obesity.
Curr Top Med Chem;
10(4): 385, 2010.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20374197
19.
Malonyl-CoA decarboxylase inhibition suppresses fatty acid oxidation and reduces lactate production during demand-induced ischemia.
Am J Physiol Heart Circ Physiol;
289(6): H2304-9, 2005 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16100246
20.
Novel chromene derivatives as TNF-alpha inhibitors.
Bioorg Med Chem Lett;
13(21): 3647-50, 2003 Nov 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14552749