Detalhe da pesquisa
1.
The complex impact of cancer-related missense mutations on the stability and on the biophysical and biochemical properties of MAPK1 and MAPK3 somatic variants.
Hum Genomics;
17(1): 95, 2023 10 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37891694
2.
Analysis and Interpretation of the Impact of Missense Variants in Cancer.
Int J Mol Sci;
22(11)2021 May 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34063805
3.
A Glimpse into the Structural Properties of the Intermediate and Transition State in the Folding of Bromodomain 2 Domain 2 by Φ Value Analysis.
Int J Mol Sci;
22(11)2021 May 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34073056
4.
Characterization of human frataxin missense variants in cancer tissues.
Hum Mutat;
40(9): 1400-1413, 2019 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31074541
5.
Evaluating the predictions of the protein stability change upon single amino acid substitutions for the FXN CAGI5 challenge.
Hum Mutat;
40(9): 1392-1399, 2019 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31209948
6.
Single-Nucleotide Polymorphism of PPARγ, a Protein at the Crossroads of Physiological and Pathological Processes.
Int J Mol Sci;
18(2)2017 Feb 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28208577
7.
Production of functional, stable, unmutated recombinant human papillomavirus E6 oncoprotein: implications for HPV-tumor diagnosis and therapy.
J Transl Med;
14(1): 224, 2016 07 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27465494
8.
Computational and experimental studies on ß-sheet breakers targeting Aß1-40 fibrils.
J Biol Chem;
289(16): 11242-11252, 2014 Apr 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24584938
9.
Structural basis of the transactivation deficiency of the human PPARγ F360L mutant associated with familial partial lipodystrophy.
Acta Crystallogr D Biol Crystallogr;
70(Pt 7): 1965-76, 2014 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25004973
10.
Mutation in the Common Docking Domain Affects MAP Kinase ERK2 Catalysis and Stability.
Cancers (Basel);
15(11)2023 May 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37296900
11.
Zn-Induced Interactions Between SARS-CoV-2 orf7a and BST2/Tetherin.
ChemistryOpen;
10(11): 1133-1141, 2021 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34791819
12.
Thermodynamic and kinetic stability of a large multi-domain enzyme from the hyperthermophile Aeropyrum pernix.
Extremophiles;
14(2): 213-23, 2010 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20058042
13.
Humanization of a highly stable single-chain antibody by structure-based antigen-binding site grafting.
Mol Immunol;
45(9): 2474-85, 2008 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18313757
14.
Dealing with Cu reduction in X-ray absorption spectroscopy experiments.
Metallomics;
11(8): 1401-1410, 2019 08 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31268088
15.
The unusual co-assembly of H- and M-chains in the ferritin molecule from the Antarctic teleosts Trematomus bernacchii and Trematomus newnesi.
Arch Biochem Biophys;
478(1): 69-74, 2008 Oct 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18625196
16.
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme.
PLoS One;
13(7): e0199191, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29995887
17.
The mutations Lys 114 --> Gln and Asp 126 --> Asn disrupt an intersubunit salt bridge and convert Listeria innocua Dps into its natural mutant Listeria monocytogenes Dps. Effects on protein stability at Low pH.
Proteins;
66(4): 975-83, 2007 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17186524
18.
Tertiary structure in 7.9 M guanidinium chloride--the role of Glu53 and Asp287 in Pyrococcus furiosus endo-beta-1,3-glucanase.
FEBS J;
274(23): 6167-79, 2007 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17999688
19.
Unveiling the folding mechanism of the Bromodomains.
Biochem Biophys Rep;
11: 99-104, 2017 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28955774
20.
PEGylated ß-Sheet Breaker Peptides as Inhibitors of ß-Amyloid Fibrillization.
Chempluschem;
82(2): 241-250, 2017 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31961555