Detalhe da pesquisa
1.
ADCT-402, a PBD dimer-containing antibody drug conjugate targeting CD19-expressing malignancies.
Blood;
131(10): 1094-1105, 2018 03 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29298756
2.
Does Activin Receptor Blockade by Bimagrumab (BYM338) Pose Detrimental Effects on Bone Healing in a Rat Fibula Osteotomy Model?
Calcif Tissue Int;
99(3): 310-21, 2016 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27167138
3.
Non-clinical Safety Evaluation of Biotherapeutics - Challenges, Opportunities and new Insights.
Regul Toxicol Pharmacol;
80S: S1-S14, 2016 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27578450
4.
ADCT-602, a Novel PBD Dimer-containing Antibody-Drug Conjugate for Treating CD22-positive Hematologic Malignancies.
Mol Cancer Ther;
23(4): 520-531, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38324336
5.
Placental transfer of Fc-containing biopharmaceuticals across species, an industry survey analysis.
Birth Defects Res B Dev Reprod Toxicol;
98(6): 459-85, 2013 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24391099
6.
Preclinical Toxicological Assessment of A Novel siRNA, SLN360, Targeting Elevated Lipoprotein (a) in Cardiovascular Disease.
Toxicol Sci;
189(2): 237-249, 2022 09 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35737426
7.
Preclinical Development of ADCT-601, a Novel Pyrrolobenzodiazepine Dimer-based Antibody-drug Conjugate Targeting AXL-expressing Cancers.
Mol Cancer Ther;
21(4): 582-593, 2022 04 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35086955
8.
CD25-targeted antibody-drug conjugate depletes regulatory T cells and eliminates established syngeneic tumors via antitumor immunity.
J Immunother Cancer;
8(2)2020 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32912922
9.
Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine.
Sci Rep;
8(1): 10479, 2018 Jul 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29992976
10.
Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody-Drug Conjugate Targeting PSMA, in Preclinical Models of Prostate Cancer.
Mol Cancer Ther;
17(10): 2176-2186, 2018 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30065100
11.
Efficacy of anti-sclerostin monoclonal antibody BPS804 in adult patients with hypophosphatasia.
J Clin Invest;
127(6): 2148-2158, 2017 Jun 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28436937
12.
Overcoming the barriers to the uptake of nonclinical microsampling in regulatory safety studies.
Drug Discov Today;
19(5): 528-32, 2014 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24448068