Detalhe da pesquisa
1.
Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins.
Cell;
153(1): 206-15, 2013 Mar 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23453757
2.
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
Cell;
153(3): 707-20, 2013 Apr 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23622250
3.
FOXM1 drives HPV+ HNSCC sensitivity to WEE1 inhibition.
Proc Natl Acad Sci U S A;
117(45): 28287-28296, 2020 11 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33093209
4.
Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and ß-TrCP.
PLoS Pathog;
15(1): e1007543, 2019 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30689667
5.
Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism.
Proc Natl Acad Sci U S A;
115(21): 5462-5467, 2018 05 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29735700
6.
The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator.
Genes Dev;
27(2): 151-6, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23322298
7.
Fbw7 dimerization determines the specificity and robustness of substrate degradation.
Genes Dev;
27(23): 2531-6, 2013 Dec 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24298052
8.
NUP50 is necessary for the survival of primordial germ cells in mouse embryos.
Reproduction;
151(1): 51-8, 2016 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26515778
9.
Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions.
PLoS Biol;
11(6): e1001586, 2013.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23776410
10.
Essential role for Cdk2 inhibitory phosphorylation during replication stress revealed by a human Cdk2 knockin mutation.
Proc Natl Acad Sci U S A;
110(22): 8954-9, 2013 May 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23671119
11.
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
J Exp Med;
204(8): 1813-24, 2007 Aug 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17646409
12.
A mouse model for cyclin E-dependent genetic instability and tumorigenesis.
Cancer Cell;
8(1): 35-47, 2005 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16023597
13.
Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor.
Sci Adv;
8(4): eabl7872, 2022 Jan 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35089787
14.
Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations.
Elife;
112022 02 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35225231
15.
Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12.
Nat Commun;
12(1): 2043, 2021 04 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33824312
16.
A mechanism misregulating p27 in tumors discovered in a functional genomic screen.
PLoS Genet;
3(12): e219, 2007 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18069898
17.
A novel landscape of nuclear human CDK2 substrates revealed by in situ phosphorylation.
Sci Adv;
6(16): eaaz9899, 2020 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32494624
18.
Cycling without CDK2?
Trends Cell Biol;
13(8): 396-9, 2003 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12888290
19.
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma.
J Cell Biol;
167(5): 925-34, 2004 Dec 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15583032
20.
Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice.
Sci Rep;
9(1): 5488, 2019 04 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30940846