Detalhe da pesquisa
1.
Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers.
Hum Mol Genet;
18(22): 4442-56, 2009 Nov 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19656774
2.
Compound I in heme thiolate enzymes: a comparative QM/MM study.
J Phys Chem A;
112(50): 13128-38, 2008 Dec 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18850694
3.
P450 enzymes: their structure, reactivity, and selectivity-modeled by QM/MM calculations.
Chem Rev;
110(2): 949-1017, 2010 Feb 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19813749
4.
Calculated and experimental spin state of seleno cytochrome P450.
Angew Chem Int Ed Engl;
48(39): 7193-5, 2009.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19718734
5.
The High-Valent Compound of Cytochrome P450: The Nature of the Fe-S Bond and the Role of the Thiolate Ligand as an Internal Electron Donor.
Angew Chem Int Ed Engl;
39(21): 3851-3855, 2000 Nov 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29711670
6.
The High-Valent Compound of Cytochrome P450: The Nature of the Fe-S Bond and the Role of the Thiolate Ligand as an Internal Electron Donor This research was sponsored in part by the Israeli Science Foundation (ISF) and the Binational German-Israeli Foundation (GIF). F.O. thanks the EU for a Marie Curie Fellowship.
Angew Chem Int Ed Engl;
40(4): 647, 2001 Feb 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11241591
7.
SULT1E1 and ID2 genes as candidates for inherited predisposition to breast and ovarian cancer in Jewish women.
Fam Cancer;
8(2): 135-44, 2009.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18821033
8.
In silico design of a mutant of cytochrome P450 containing selenocysteine.
J Am Chem Soc;
128(8): 2649-53, 2006 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16492051
9.
Does substrate oxidation determine the regioselectivity of cyclohexene and propene oxidation by cytochrome p450?
J Am Chem Soc;
128(34): 11028-9, 2006 Aug 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16925412
10.
Principal active species of horseradish peroxidase, compound I: a hybrid quantum mechanical/molecular mechanical study.
J Am Chem Soc;
127(39): 13611-21, 2005 Oct 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16190726
11.
Searching for the second oxidant in the catalytic cycle of cytochrome P450: a theoretical investigation of the iron(III)-hydroperoxo species and its epoxidation pathways.
J Am Chem Soc;
124(11): 2806-17, 2002 Mar 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11890833
12.
Quantum mechanical/molecular mechanical investigation of the mechanism of C-H hydroxylation of camphor by cytochrome P450cam: theory supports a two-state rebound mechanism.
J Am Chem Soc;
126(12): 4017-34, 2004 Mar 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15038756
13.
Radical clock substrates, their C-H hydroxylation mechanism by cytochrome P450, and other reactivity patterns: what does theory reveal about the clocks' behavior?
J Am Chem Soc;
126(6): 1907-20, 2004 Feb 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14871124
14.
A predictive pattern of computed barriers for C-h hydroxylation by compound I of cytochrome p450.
J Am Chem Soc;
126(27): 8362-3, 2004 Jul 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15237977
15.
The elusive oxidant species of cytochrome P450 enzymes: characterization by combined quantum mechanical/molecular mechanical (QM/MM) calculations.
J Am Chem Soc;
124(27): 8142-51, 2002 Jul 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12095360