Detalhe da pesquisa
1.
Rescue of GSDIII Phenotype with Gene Transfer Requires Liver- and Muscle-Targeted GDE Expression.
Mol Ther;
26(3): 890-901, 2018 03 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29396266
2.
Understanding and Tackling Immune Responses to Adeno-Associated Viral Vectors.
Hum Gene Ther;
34(17-18): 836-852, 2023 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37672519
3.
Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates.
Nat Commun;
12(1): 6393, 2021 11 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34737297
4.
Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses.
Sci Transl Med;
13(580)2021 02 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33568518
5.
Role of Regulatory T Cell and Effector T Cell Exhaustion in Liver-Mediated Transgene Tolerance in Muscle.
Mol Ther Methods Clin Dev;
15: 83-100, 2019 Dec 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31649958
6.
AAV Gene Transfer with Tandem Promoter Design Prevents Anti-transgene Immunity and Provides Persistent Efficacy in Neonate Pompe Mice.
Mol Ther Methods Clin Dev;
12: 85-101, 2019 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30581888
7.
Exposure to wild-type AAV drives distinct capsid immunity profiles in humans.
J Clin Invest;
128(12): 5267-5279, 2018 12 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30352429
8.
Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration.
Nat Commun;
9(1): 4098, 2018 10 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30291246
9.
Cellular uptake of extracellular vesicles is mediated by clathrin-independent endocytosis and macropinocytosis.
J Control Release;
266: 100-108, 2017 Nov 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28919558