Detalhe da pesquisa
1.
Proteomic Profiling of Antimalarial Plasmodione Using 3-Benz(o)ylmenadione Affinity-Based Probes.
Chembiochem;
: e202400187, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38639212
2.
Synthesis and Photochemical Properties of Fluorescent Metabolites Generated from Fluorinated Benzoylmenadiones in Living Cells.
J Org Chem;
89(4): 2104-2126, 2024 02 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37267444
3.
Chemoselective Synthesis and Anti-Kinetoplastidal Properties of 2,6-Diaryl-4H-tetrahydro-thiopyran-4-one S-Oxides: Their Interplay in a Cascade of Redox Reactions from Diarylideneacetones.
Molecules;
29(7)2024 Apr 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38611899
4.
Bioinspired Photoredox Benzylation of Quinones.
J Org Chem;
86(15): 10055-10066, 2021 08 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34264092
5.
A Mild and Versatile Friedel-Crafts Methodology for the Diversity-Oriented Synthesis of Redox-Active 3-Benzoylmenadiones with Tunable Redox Potentials.
Chemistry;
26(15): 3314-3325, 2020 Mar 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31746499
6.
Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections.
Molecules;
25(21)2020 Nov 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33139647
7.
Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase.
Molecules;
24(24)2019 Dec 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31835450
8.
A high susceptibility to redox imbalance of the transmissible stages of Plasmodium falciparum revealed with a luciferase-based mature gametocyte assay.
Mol Microbiol;
104(2): 306-318, 2017 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28118506
9.
Synthesis of plasmodione metabolites and 13C-enriched plasmodione as chemical tools for drug metabolism investigation.
Org Biomol Chem;
16(15): 2647-2665, 2018 04 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29542786
10.
QSAR modeling and chemical space analysis of antimalarial compounds.
J Comput Aided Mol Des;
31(5): 441-451, 2017 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28374255
11.
Pharmacomodulation of the Antimalarial Plasmodione: Synthesis of Biaryl- and N-Arylalkylamine Analogues, Antimalarial Activities and Physicochemical Properties.
Molecules;
22(1)2017 Jan 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28106855
12.
The Redox Cycler Plasmodione Is a Fast-Acting Antimalarial Lead Compound with Pronounced Activity against Sexual and Early Asexual Blood-Stage Parasites.
Antimicrob Agents Chemother;
60(9): 5146-58, 2016 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27297478
13.
In Silico Mining for Antimalarial Structure-Activity Knowledge and Discovery of Novel Antimalarial Curcuminoids.
Molecules;
21(7)2016 Jun 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27367660
14.
Electrochemical properties of substituted 2-methyl-1,4-naphthoquinones: redox behavior predictions.
Chemistry;
21(8): 3415-24, 2015 Feb 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25556761
15.
Synthesis and Anti-Chagas Activity Profile of a Redox-Active Lead 3-Benzylmenadione Revealed by High-Content Imaging.
ACS Infect Dis;
10(5): 1808-1838, 2024 05 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38606978
16.
The antimalarial activities of methylene blue and the 1,4-naphthoquinone 3-[4-(trifluoromethyl)benzyl]-menadione are not due to inhibition of the mitochondrial electron transport chain.
Antimicrob Agents Chemother;
57(5): 2114-20, 2013 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23439633
17.
A plant-derived flavonoid inhibits entry of all HCV genotypes into human hepatocytes.
Gastroenterology;
143(1): 213-22.e5, 2012 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22465429
18.
Exploring the trifluoromenadione core as a template to design antimalarial redox-active agents interacting with glutathione reductase.
Org Biomol Chem;
10(24): 4795-806, 2012 Jun 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22618151
19.
Synthesis and biological evaluation of 1,4-naphthoquinones and quinoline-5,8-diones as antimalarial and schistosomicidal agents.
Org Biomol Chem;
10(31): 6375-87, 2012 Aug 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22777178
20.
Evaluation of ferrocenyl-containing γ-hydroxy-γ-lactam-derived tetramates as potential antiplasmodials.
Eur J Med Chem;
243: 114735, 2022 Dec 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36122550