Detalhe da pesquisa
1.
Trial of Solanezumab for Mild Dementia Due to Alzheimer's Disease.
N Engl J Med;
378(4): 321-330, 2018 01 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29365294
2.
Adaptation of the robust method to large distributions of reference values: program modifications and comparison of alternative computational methods.
J Biopharm Stat;
29(3): 516-528, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30757951
3.
The impact of preanalytical variables on measuring cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: A review.
Alzheimers Dement;
14(10): 1313-1333, 2018 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29940161
4.
The potent BACE1 inhibitor LY2886721 elicits robust central Aß pharmacodynamic responses in mice, dogs, and humans.
J Neurosci;
35(3): 1199-210, 2015 Jan 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25609634
5.
Phase 3 solanezumab trials: Secondary outcomes in mild Alzheimer's disease patients.
Alzheimers Dement;
12(2): 110-120, 2016 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26238576
6.
Florbetapir positron emission tomography and cerebrospinal fluid biomarkers.
Alzheimers Dement;
11(8): 986-93, 2015 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25916563
7.
The Alzheimer's Disease Neuroimaging Initiative 2 Biomarker Core: A review of progress and plans.
Alzheimers Dement;
11(7): 772-91, 2015 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26194312
8.
Effects of duloxetine on norepinephrine and serotonin transporter activity in healthy subjects.
J Clin Psychopharmacol;
34(1): 9-16, 2014 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24346757
9.
A phase 2, placebo-controlled study of the opioid receptor antagonist LY2196044 for the treatment of alcohol dependence.
Alcohol Clin Exp Res;
38(2): 511-20, 2014 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24010675
10.
Revisiting the framework of the National Institute on Aging-Alzheimer's Association diagnostic criteria.
Alzheimers Dement;
9(5): 594-601, 2013 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24007744
11.
Robust central reduction of amyloid-ß in humans with an orally available, non-peptidic ß-secretase inhibitor.
J Neurosci;
31(46): 16507-16, 2011 Nov 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22090477
12.
Safety and biomarker effects of solanezumab in patients with Alzheimer's disease.
Alzheimers Dement;
8(4): 261-71, 2012 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22672770
13.
Robust Pharmacodynamic Effect of LY3202626, a Central Nervous System Penetrant, Low Dose BACE1 Inhibitor, in Humans and Nonclinical Species.
J Alzheimers Dis Rep;
6(1): 1-15, 2022.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35243208
14.
N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes.
J Pharmacol Exp Ther;
336(1): 165-77, 2011 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20947638
15.
Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI.
Acta Neuropathol;
121(5): 597-609, 2011 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21311900
16.
Hydrothermal carbonization of simulated food waste for recovery of fatty acids and nutrients.
Bioresour Technol;
341: 125872, 2021 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34523573
17.
Anti-Aß antibody target engagement: commentary regarding Watt et al. Acta Neuropathol 127:803-810 (2014).
Acta Neuropathol;
128(4): 609-10, 2014 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25120192
18.
Proteomics of cerebrospinal fluid: methods for sample processing.
Methods Mol Biol;
425: 53-66, 2008.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18369886
19.
Central pharmacodynamic activity of solanezumab in mild Alzheimer's disease dementia.
Alzheimers Dement (N Y);
4: 652-660, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30511011
20.
Derivation of cutoffs for the Elecsys® amyloid ß (1-42) assay in Alzheimer's disease.
Alzheimers Dement (Amst);
10: 698-705, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30426066