Detalhe da pesquisa
1.
Antigiardial and antiamebic activities of fexinidazole and its metabolites: new drug leads for giardiasis and amebiasis.
Antimicrob Agents Chemother;
68(1): e0073123, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38063401
2.
A Smartphone-Based Detection System for Tomato Leaf Disease Using EfficientNetV2B2 and Its Explainability with Artificial Intelligence (AI).
Sensors (Basel);
23(21)2023 Oct 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37960385
3.
Domain-Swap Dimerization of Acanthamoeba castellanii CYP51 and a Unique Mechanism of Inactivation by Isavuconazole.
Mol Pharmacol;
98(6): 770-780, 2020 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33008918
4.
The Antifungal Drug Isavuconazole Is both Amebicidal and Cysticidal against Acanthamoeba castellanii.
Antimicrob Agents Chemother;
64(5)2020 04 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32094126
5.
Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri.
PLoS Pathog;
14(9): e1007245, 2018 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30212566
6.
Susceptibility Testing of Medically Important Parasites.
Clin Microbiol Rev;
30(3): 647-669, 2017 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28446445
7.
Identification of cysteine protease inhibitors as new drug leads against Naegleria fowleri.
Exp Parasitol;
188: 36-41, 2018 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29551628
8.
X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action.
J Struct Biol;
194(2): 180-90, 2016 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26876147
9.
In vitro efficacy of corifungin against Acanthamoeba castellanii trophozoites and cysts.
Antimicrob Agents Chemother;
58(3): 1523-8, 2014.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24366747
10.
Hsp90 inhibitors as new leads to target parasitic diarrheal diseases.
Antimicrob Agents Chemother;
58(7): 4138-44, 2014 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24820073
11.
A reprofiled drug, auranofin, is effective against metronidazole-resistant Giardia lamblia.
Antimicrob Agents Chemother;
57(5): 2029-35, 2013 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23403423
12.
High-Throughput Screen of Microbial Metabolites Identifies F1FO ATP Synthase Inhibitors as New Leads for Naegleria fowleri Infection.
ACS Infect Dis;
9(12): 2622-2631, 2023 Dec 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37943251
13.
Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors.
J Med Chem;
66(24): 17059-17073, 2023 12 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38085955
14.
Corifungin, a new drug lead against Naegleria, identified from a high-throughput screen.
Antimicrob Agents Chemother;
56(11): 5450-7, 2012 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22869574
15.
Development of a Machine Learning-Based Cysticidal Assay and Identification of an Amebicidal and Cysticidal Marine Microbial Metabolite against Acanthamoeba.
Microbiol Spectr;
10(3): e0007722, 2022 06 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35467370
16.
A Bioluminescence-Based Drug Screen Identifies Activities of Fexinidazole and Its Metabolites against Helicobacter pylori.
Antibiotics (Basel);
11(11)2022 Nov 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36421252
17.
A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using Leishmania donovani.
Pathogens;
11(12)2022 Nov 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36558759
18.
Drug discovery for primary amebic meningoencephalitis: from screen to identification of leads.
Expert Rev Anti Infect Ther;
19(9): 1099-1106, 2021 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33496193
19.
Evaluation of Amebicidal and Cysticidal Activities of Antifungal Drug Isavuconazonium Sulfate against Acanthamoeba T4 Strains.
Pharmaceuticals (Basel);
14(12)2021 Dec 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34959694
20.
Antineoplastic kinase inhibitors: A new class of potent anti-amoebic compounds.
PLoS Negl Trop Dis;
15(2): e0008425, 2021 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33556060