Detalhe da pesquisa
1.
Identification of BiP as a CB1 Receptor-Interacting Protein That Fine-Tunes Cannabinoid Signaling in the Mouse Brain.
J Neurosci;
41(38): 7924-7941, 2021 09 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34353897
2.
Therapeutic targeting of HER2-CB2R heteromers in HER2-positive breast cancer.
Proc Natl Acad Sci U S A;
116(9): 3863-3872, 2019 02 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30733293
3.
Adrenergic Modulation With Photochromic Ligands.
Angew Chem Int Ed Engl;
60(7): 3625-3631, 2021 02 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33103317
4.
Ligand bias and inverse agonism on 5-HT2A receptor-mediated modulation of G protein activity in post-mortem human brain.
Br J Pharmacol;
2024 Apr 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38644550
5.
Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression and epigenetic control in postmortem brains of schizophrenia subjects.
Transl Psychiatry;
14(1): 113, 2024 Feb 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38396013
6.
The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls.
EMBO Mol Med;
16(4): 755-783, 2024 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38514794
7.
G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits.
Nat Commun;
15(1): 4307, 2024 May 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38811567
8.
Design, Synthesis, Molecular Docking, and Biological Evaluation of Novel Pimavanserin-Based Analogues as Potential Serotonin 5-HT2A Receptor Inverse Agonists.
J Med Chem;
66(13): 9057-9075, 2023 07 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37378639
9.
Selective inhibition of cannabinoid CB1 receptor-evoked signalling by the interacting protein GAP43.
Neuropharmacology;
240: 109712, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37689260
10.
Isolation and Differentiation of Neurons and Glial Cells from Olfactory Epithelium in Living Subjects.
Mol Neurobiol;
60(8): 4472-4487, 2023 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37118325
11.
Serotonin 2A receptors and cannabinoids.
Prog Brain Res;
259: 135-175, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33541675
12.
Characterization of dopamine D2 receptor coupling to G proteins in postmortem brain of subjects with schizophrenia.
Pharmacol Rep;
73(4): 1136-1146, 2021 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34196951
13.
α2A- and α2C-adrenoceptor expression and functionality in postmortem prefrontal cortex of schizophrenia subjects.
Eur Neuropsychopharmacol;
52: 3-11, 2021 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34237656
14.
Functional approaches to the study of G-protein-coupled receptors in postmortem brain tissue: [35S]GTPγS binding assays combined with immunoprecipitation.
Pharmacol Rep;
73(4): 1079-1095, 2021 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33876404
15.
Opposite alterations of 5-HT2A receptor brain density in subjects with schizophrenia: relevance of radiotracers pharmacological profile.
Transl Psychiatry;
11(1): 302, 2021 05 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34016955
16.
Pimavanserin exhibits serotonin 5-HT2A receptor inverse agonism for Gαi1- and neutral antagonism for Gαq/11-proteins in human brain cortex.
Eur Neuropsychopharmacol;
36: 83-89, 2020 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32517960
17.
Ribosomal Protein S6 Hypofunction in Postmortem Human Brain Links mTORC1-Dependent Signaling and Schizophrenia.
Front Pharmacol;
11: 344, 2020.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32265715
18.
Chronic fluoxetine reverses the effects of chronic corticosterone treatment on α2-adrenoceptors in the rat frontal cortex but not locus coeruleus.
Neuropharmacology;
158: 107731, 2019 11 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31376424
19.
Big Data Challenges Targeting Proteins in GPCR Signaling Pathways; Combining PTML-ChEMBL Models and [35S]GTPγS Binding Assays.
ACS Chem Neurosci;
10(11): 4476-4491, 2019 11 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31618004
20.
Serotonin 5-HT2A receptor expression and functionality in postmortem frontal cortex of subjects with schizophrenia: Selective biased agonism via Gαi1-proteins.
Eur Neuropsychopharmacol;
29(12): 1453-1463, 2019 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31734018