Detalhe da pesquisa
1.
Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease.
Blood;
138(17): 1554-1569, 2021 10 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34077954
2.
Regulation of the microtubular cytoskeleton by Polycystin-1 favors focal adhesions turnover to modulate cell adhesion and migration.
BMC Cell Biol;
16: 15, 2015 May 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25947155
3.
Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression.
EMBO Mol Med;
16(6): 1379-1403, 2024 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38684863
4.
Primary cilia sense glutamine availability and respond via asparagine synthetase.
Nat Metab;
5(3): 385-397, 2023 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36879119
5.
Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion.
Mol Biol Cell;
18(10): 4050-61, 2007 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17671167
6.
Polycystin-1 Regulates Actomyosin Contraction and the Cellular Response to Extracellular Stiffness.
Sci Rep;
9(1): 16640, 2019 11 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31719603
7.
Dissection of metabolic reprogramming in polycystic kidney disease reveals coordinated rewiring of bioenergetic pathways.
Commun Biol;
1: 194, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30480096
8.
Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis.
Nat Commun;
4: 2658, 2013.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24153433
9.
Nephrocystin-1 forms a complex with polycystin-1 via a polyproline motif/SH3 domain interaction and regulates the apoptotic response in mammals.
PLoS One;
5(9): e12719, 2010 Sep 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20856870
10.
Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1.
Mol Cell Biol;
29(9): 2359-71, 2009 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19255143
11.
Polycystin-1 induces resistance to apoptosis through the phosphatidylinositol 3-kinase/Akt signaling pathway.
J Am Soc Nephrol;
17(3): 637-47, 2006 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16452497