Tribo-Mechanical Investigation of Glass Fiber Reinforced Polymer Composites under Dry Conditions.

Tribo-mechanical experiments were performed on Glass Fiber Reinforced Polymer (GRFP) composites against different engineering materials, and the tribological behavior of these materials under dry conditions was investigated. The novelty of this study consists of the investigation of the tribomechanical properties of a customized GFRP/epoxy composite, different from those identified in the literature. The investigated material in the work is composed of 270 g/m2 fiberglass twill fabric/epoxy matrix. It was manufactured by the vacuum bag method and autoclave curing procedure. The goal was to define the tribo-mechanical characteristics of a 68.5% weight fraction ratio (wf) of GFRP composites in relation to the different categories of plastic materials, alloyed steel, and technical ceramics. The properties of the material, including ultimate tensile strength, Young's modulus of elasticity, elastic strain, and impact strength of the GFPR, were determined through standard tests. The friction coefficients were obtained using a modified pin-on-disc tribometer using sliding speeds ranging from 0.1 to 0.36 m s-1, load 20 N, and different counter face balls from Polytetrafluoroethylene (PTFE), Polyamide (Torlon), 52,100 Chrome Alloy Steel, 440 Stainless Steel, and Ceramic Al2O3, with 12.7 mm in diameter, in dry conditions. These are commonly used as ball and roller bearings in industry and for a variety of automotive applications. To evaluate the wear mechanisms, the worm surfaces were examined and investigated by a Nano Focus-Optical 3D Microscopy, which uses cutting-edge µsurf technology to provide highly accurate 3D measurements of surfaces. The obtained results constitute an important database for the tribo-mechanical behavior of this engineering GFRP composite material.

Salivary Biomarkers of Anti-Epileptic Drugs: A Narrative Review.

Saliva is a biofluid that reflects general health and that can be collected in order to evaluate and determine various pathologies and treatments. Biomarker analysis through saliva sampling is an emerging method of accurately screening and diagnosing diseases. Anti-epileptic drugs (AEDs) are prescribed generally in seizure treatment. The dose-response relationship of AEDs is influenced by numerous factors and varies from patient to patient, hence the need for the careful supervision of drug intake. The therapeutic drug monitoring (TDM) of AEDs was traditionally performed through repeated blood withdrawals. Saliva sampling in order to determine and monitor AEDs is a novel, fast, low-cost and non-invasive approach. This narrative review focuses on the characteristics of various AEDs and the possibility of determining active plasma concentrations from saliva samples. Additionally, this study aims to highlight the significant correlations between AED blood, urine and oral fluid levels and the applicability of saliva TDM for AEDs. The study also focuses on emphasizing the applicability of saliva sampling for epileptic patients.

Numerical Investigation of the Infill Rate upon Mechanical Proprieties of 3D-Printed Materials.

The paper proposes a novel method of numerical simulation of the fused deposition molding 3Dprinted parts. The single filaments are modeled by a script using the G-code of the 3D printer. Based on experimental evaluation of the cross-sectional geometry of a printed tensile specimen, the connection between the filaments is determined and the flattening effect of the filaments can be counted. Finite element (FE) simulations considering different element lengths were validated by experimental tests. The methodology allows, on one hand, numerical estimation of the true cross-sectional area of a specimen and correction of the experimental stress-strain curves and, on the other hand, accurate determination of the E-modulus of a printed tensile specimen with different deposition densities (20%, 40%, 60%, 80% and 100% infill rate). If the right method to connect the single filaments is established and validated for a 3D printer, the mechanical properties of the 3D specimens can be predicted without physical tensile test, only using FE method, which will allow the designers to print out the parts with variable infill rate and tunable stiffness only after the FE result are suitable for their needs, saving considerably materials and time.

Evaluation of Bond Strength of Four Different Root Canal Sealers.

The purposes of the study were to evaluate the influence of the sealer's chemical composition on the interfacial strength between root canal dentin and root filling material, for two different classes of endodontic sealers, and to assess their failure modes. Methods: Forty extracted single-rooted teeth were randomly divided into four groups using the following endodontic sealers: RealSeal SE and Resilon (RSSE); EndoSequence BC sealer and BC Point (EBCS); Endoseal MTA and gutta-percha (EDS); Bioroot RCS and gutta-percha (BRS). Teeth were embedded in acrylic resin, and the roots were sectioned horizontally into 1 mm slices. For each slice, the perimeter was measured. A push-out test was performed using an Instron universal testing machine. For each sample, bond strength was calculated. Specimens were examined by SEM investigation in order to analyze the dentin−sealer−core interface. Results were assessed using analysis of variance (ANOVA) and Tukey and Bonferroni test. Results: Statistical analysis revealed that EDS and gutta-percha had significantly higher resistance to dislodgement compared to the other three groups (p < 0.05). EBCS and BC Point showed significantly greater push-out bond strength values compared to RSSE and Resilon (p < 0.05). Conclusions: Bioceramic endodontic sealers showed a higher bond strength to root dentin than methacrylate resin-based endodontic sealer.

Optimization of Moist and Oven-Dried Bacterial Cellulose Production for Functional Properties.

Bacterial cellulose (BC) is a natural polymer with properties suitable for tissue engineering and possible applications in scaffold production. However, current procedures have limitations in obtaining BC pellicles with the desired structural, physical, and mechanical properties. Thus, this study analyzed the optimal culture conditions of BC membranes and two types of processing: draining and oven-drying. The aim was to obtain BC membranes with properties suitable for a wound dressing material. Two studies were carried out. In the preliminary study, the medium (100 mL) was inoculated with varying volumes (1, 2, 3, 4, and 5 mL) and incubated statically for different periods (3, 6, 9, 12, and 18 days), using a full factorial experimental design. Thickness, uniformity, weight, and yield were evaluated. In the optimization study, a Box-Behnken design was used. Two independent variables were used: inoculum volume (X1: 1, 3, and 5 mL) and fermentation period (X2: 6, 12, and 18 d) to determine the target response variables: thickness, swelling ratio, drug release, fiber diameter, tensile strength, and Young's modulus for both dry and moist BC membranes. The mathematical modelling of the effect of the two independent variables was performed by response surface methodology (RSM). The obtained models were validated with new experimental values and confirmed for all tested properties, except Young's modulus of oven-dried BC. Thus, the optimal properties in terms of a scaffold material of the moist BC were obtained with an inoculum volume of 5% (v/v) and 16 d of fermentation. While, for the oven-dried membranes, optimal properties were obtained with a 4% (v/v) and 14 d of fermentation.

Correction: Bodea et al. Optimization of Moist and Oven-Dried Bacterial Cellulose Production for Functional Properties. Polymers 2021, 13, 2088.

The authors wish to make a change to the published paper [...].