Detalhe da pesquisa
1.
Rationale for targeting BCL6 in MLL-rearranged acute lymphoblastic leukemia.
Genes Dev;
33(17-18): 1265-1279, 2019 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31395741
2.
The burden of disease due to COVID-19 in Sweden 2020-2021: A disability-adjusted life years (DALYs) study.
Scand J Public Health;
51(5): 673-681, 2023 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36941820
3.
MLL1 Promotes IL-7 Responsiveness and Survival during B Cell Differentiation.
J Immunol;
200(5): 1682-1691, 2018 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29351999
4.
Distinct functions of histone H3, lysine 4 methyltransferases in normal and malignant hematopoiesis.
Curr Opin Hematol;
24(4): 322-328, 2017 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28375985
5.
Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory.
J Neurosci;
35(13): 5097-108, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25834037
6.
An MLL-dependent network sustains hematopoiesis.
Proc Natl Acad Sci U S A;
110(29): 12000-5, 2013 Jul 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23744037
7.
Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells.
Blood;
122(12): 2039-46, 2013 Sep 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23908472
8.
Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells.
Nature;
458(7237): 529-33, 2009 Mar 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19212323
9.
Acat1 gene ablation in mice increases hematopoietic progenitor cell proliferation in bone marrow and causes leukocytosis.
Arterioscler Thromb Vasc Biol;
33(9): 2081-7, 2013 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23846496
10.
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes.
Nat Cell Biol;
25(2): 258-272, 2023 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36635503
11.
Using human pluripotent stem cells to untangle neurodegenerative disease mechanisms.
Cell Mol Life Sci;
68(4): 635-49, 2011 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20976521
12.
Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation.
iScience;
25(1): 103679, 2022 Jan 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35036869
13.
Does lineage plasticity enable escape from CAR-T cell therapy? Lessons from MLL-r leukemia.
Exp Hematol;
100: 1-11, 2021 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34298117
14.
Menin is necessary for long term maintenance of meningioma-1 driven leukemia.
Leukemia;
35(5): 1405-1417, 2021 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33542482
15.
Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity.
Nat Commun;
12(1): 2792, 2021 05 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33990599
16.
cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes.
Nature;
425(6955): 300-6, 2003 Sep 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-13679919
17.
Enhancing Hematopoiesis from Murine Embryonic Stem Cells through MLL1-Induced Activation of a Rac/Rho/Integrin Signaling Axis.
Stem Cell Reports;
14(2): 285-299, 2020 02 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31951812
18.
Definitive hematopoiesis requires the mixed-lineage leukemia gene.
Dev Cell;
6(3): 437-43, 2004 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15030765
19.
Hematopoietic transformation in the absence of MLL1/KMT2A: distinctions in target gene reactivation.
Cell Cycle;
18(14): 1525-1531, 2019 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31161857
20.
Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.
Exp Hematol;
69: 37-42, 2019 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30315824