Detalhe da pesquisa
1.
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Cell;
186(22): 4898-4919.e25, 2023 10 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37827155
2.
Single nuclei RNA-seq reveals a medium spiny neuron glutamate excitotoxicity signature prior to the onset of neuronal death in an ovine Huntington's disease model.
Hum Mol Genet;
2024 May 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38776957
3.
Hippocampal aggregation signatures of pathogenic UBQLN2 in amyotrophic lateral sclerosis and frontotemporal dementia.
Brain;
2024 May 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38703371
4.
A panel of TDP-43-regulated splicing events verifies loss of TDP-43 function in amyotrophic lateral sclerosis brain tissue.
Neurobiol Dis;
185: 106245, 2023 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37527763
5.
The amyotrophic lateral sclerosis-linked protein TDP-43 regulates interleukin-6 cytokine production by human brain pericytes.
Mol Cell Neurosci;
123: 103768, 2022 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36038081
6.
ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function.
Proc Natl Acad Sci U S A;
117(26): 15230-15241, 2020 06 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32513711
7.
Is Hormone Replacement Therapy a Risk Factor or a Therapeutic Option for Alzheimer's Disease?
Int J Mol Sci;
24(4)2023 Feb 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36834617
8.
Cation-Chloride Cotransporters KCC2 and NKCC1 as Therapeutic Targets in Neurological and Neuropsychiatric Disorders.
Molecules;
28(3)2023 Jan 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36771011
9.
N-terminal mutant huntingtin deposition correlates with CAG repeat length and symptom onset, but not neuronal loss in Huntington's disease.
Neurobiol Dis;
174: 105884, 2022 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36220612
10.
Neuroprotective Effect of Caffeine in Alzheimer's Disease.
Molecules;
27(12)2022 Jun 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35744865
11.
Beta-Amyloid (Aß1-42) Increases the Expression of NKCC1 in the Mouse Hippocampus.
Molecules;
27(8)2022 Apr 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35458638
12.
An imaging mass spectrometry atlas of lipids in the human neurologically normal and Huntington's disease caudate nucleus.
J Neurochem;
157(6): 2158-2172, 2021 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33606279
13.
fISHing with immunohistochemistry for housekeeping gene changes in Alzheimer's disease using an automated quantitative analysis workflow.
J Neurochem;
157(4): 1270-1283, 2021 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33368239
14.
Neuroimaging and neuropathology studies of X-linked dystonia parkinsonism.
Neurobiol Dis;
148: 105186, 2021 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33227492
15.
Promise and challenges of dystonia brain banking: establishing a human tissue repository for studies of X-Linked Dystonia-Parkinsonism.
J Neural Transm (Vienna);
128(4): 575-587, 2021 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33439365
16.
Amyloid-beta1-42 induced glutamatergic receptor and transporter expression changes in the mouse hippocampus.
J Neurochem;
155(1): 62-80, 2020 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32491248
17.
Inconsistencies in histone acetylation patterns among different HD model systems and HD post-mortem brains.
Neurobiol Dis;
146: 105092, 2020 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32979507
18.
Cerebral deficiency of vitamin B5 (d-pantothenic acid; pantothenate) as a potentially-reversible cause of neurodegeneration and dementia in sporadic Alzheimer's disease.
Biochem Biophys Res Commun;
527(3): 676-681, 2020 06 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32416962
19.
Cerebellar degeneration correlates with motor symptoms in Huntington disease.
Ann Neurol;
85(3): 396-405, 2019 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30635944
20.
Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases.
Proc Natl Acad Sci U S A;
114(52): E11293-E11302, 2017 12 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29229845