Detalhe da pesquisa
1.
NFAT5, which protects against hypertonicity, is activated by that stress via structuring of its intrinsically disordered domain.
Proc Natl Acad Sci U S A;
117(33): 20292-20297, 2020 08 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32747529
2.
Peptide affinity analysis of proteins that bind to an unstructured NH2-terminal region of the osmoprotective transcription factor NFAT5.
Physiol Genomics;
48(4): 290-305, 2016 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26757802
3.
Peptide affinity analysis of proteins that bind to an unstructured region containing the transactivating domain of the osmoprotective transcription factor NFAT5.
Physiol Genomics;
48(11): 835-849, 2016 11 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27764768
4.
High NaCl- and urea-induced posttranslational modifications that increase glycerophosphocholine by inhibiting GDPD5 phosphodiesterase.
Proc Natl Acad Sci U S A;
110(18): 7482-7, 2013 Apr 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23589856
5.
RNA-Seq analysis of high NaCl-induced gene expression.
Physiol Genomics;
47(10): 500-13, 2015 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26220925
6.
PKC-α contributes to high NaCl-induced activation of NFAT5 (TonEBP/OREBP) through MAPK ERK1/2.
Am J Physiol Renal Physiol;
308(2): F140-8, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25391900
7.
Expression, fermentation and purification of a predicted intrinsically disordered region of the transcription factor, NFAT5.
Protein Expr Purif;
115: 141-5, 2015 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26256058
8.
Global discovery of high-NaCl-induced changes of protein phosphorylation.
Am J Physiol Cell Physiol;
307(5): C442-54, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24965592
9.
Rac1/osmosensing scaffold for MEKK3 contributes via phospholipase C-gamma1 to activation of the osmoprotective transcription factor NFAT5.
Proc Natl Acad Sci U S A;
108(29): 12155-60, 2011 Jul 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21712438
10.
Inhibitory phosphorylation of GSK-3ß by AKT, PKA, and PI3K contributes to high NaCl-induced activation of the transcription factor NFAT5 (TonEBP/OREBP).
Am J Physiol Renal Physiol;
304(7): F908-17, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23324178
11.
High NaCl-induced inhibition of PTG contributes to activation of NFAT5 through attenuation of the negative effect of SHP-1.
Am J Physiol Renal Physiol;
305(3): F362-9, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23720348
12.
Contribution of SHP-1 protein tyrosine phosphatase to osmotic regulation of the transcription factor TonEBP/OREBP.
Proc Natl Acad Sci U S A;
107(15): 7072-7, 2010 Apr 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20351292
13.
Phospholipase C-gamma1 is involved in signaling the activation by high NaCl of the osmoprotective transcription factor TonEBP/OREBP.
Proc Natl Acad Sci U S A;
107(2): 906-11, 2010 Jan 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20080774
14.
Mutations that reduce its specific DNA binding inhibit high NaCl-induced nuclear localization of the osmoprotective transcription factor NFAT5.
Am J Physiol Cell Physiol;
303(10): C1061-9, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22992674
15.
Proteomic analysis of high NaCl-induced changes in abundance of nuclear proteins.
Physiol Genomics;
44(21): 1063-71, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22991206
16.
Water restriction increases renal inner medullary manganese superoxide dismutase (MnSOD).
Am J Physiol Renal Physiol;
303(5): F674-80, 2012 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22718889
17.
c-Abl mediates high NaCl-induced phosphorylation and activation of the transcription factor TonEBP/OREBP.
FASEB J;
24(11): 4325-35, 2010 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20585028
18.
GDPD5 is a glycerophosphocholine phosphodiesterase that osmotically regulates the osmoprotective organic osmolyte GPC.
Proc Natl Acad Sci U S A;
105(31): 11026-31, 2008 Aug 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18667693
19.
MKP-1 inhibits high NaCl-induced activation of p38 but does not inhibit the activation of TonEBP/OREBP: opposite roles of p38alpha and p38delta.
Proc Natl Acad Sci U S A;
105(14): 5620-5, 2008 Apr 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18367666
20.
Salt, skeletons, and suicide. Focus on "Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton".
Am J Physiol Cell Physiol;
304(2): C113-4, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23099642