Detalhe da pesquisa
1.
Evaluating the Use of Antibody Variable Region (Fv) Charge as a Risk Assessment Tool for Predicting Typical Cynomolgus Monkey Pharmacokinetics.
J Biol Chem;
290(50): 29732-41, 2015 Dec 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26491012
2.
Lebrikizumab in moderate-to-severe asthma: pooled data from two randomised placebo-controlled studies.
Thorax;
70(8): 748-56, 2015 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26001563
3.
Expanding assay range to accommodate a monoclonal antibody therapeutic quantification in blood and cerebrospinal fluid.
Bioanalysis;
16(3): 129-140, 2024 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38088824
4.
Successful Development of Nonclinical Anti-Drug Antibody Assays to Support Zinpentraxin Alfa Reproductive Toxicology Studies.
AAPS J;
26(1): 16, 2024 01 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38267613
5.
Overcoming Soluble Target Interference in Measurement of Total Bispecific Therapeutic Antibody Concentrations.
AAPS J;
25(5): 82, 2023 08 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37594571
6.
Factors contributing to the nonlinear pharmacokinetics of astegolimab: a close examination of potential causes.
Bioanalysis;
15(21): 1305-1314, 2023 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37791725
7.
Validation of low-volume sampling devices for pharmacokinetic analysis: technical and logistical challenges and solutions.
Bioanalysis;
15(23): 1407-1419, 2023 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37855111
8.
The Development and Characterization of a Highly Sensitive Mature TGFß3 Assay to Evaluate Anti-TGFß3 Target Engagement.
AAPS J;
25(1): 21, 2023 01 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36703086
9.
Novel Selective Quantification of Zinpentraxin Alfa Biotherapeutic in the Presence of Endogenous Isomer in Plasma Samples of Idiopathic Pulmonary Fibrosis Patients Using Immunoaffinity LC-MS.
AAPS J;
26(1): 9, 2023 12 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38114736
10.
Challenges with development of a pharmacokinetics assay to measure a variably glycosylated fusion protein.
Bioanalysis;
14(1): 7-18, 2022 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34789009
11.
Assessment of low volume sampling technologies: utility in nonclinical and clinical studies.
Bioanalysis;
13(9): 679-691, 2021 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33900106
12.
Evaluation of two point of care technologies for measuring monoclonal antibody therapeutic-A concentrations in blood.
Bioanalysis;
12(20): 1449-1458, 2020 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32975432
13.
Development of a specific immunoassay to selectively measure active tryptase in airway samples.
Bioanalysis;
12(19): 1377-1388, 2020 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32975431
14.
Bioanalytical challenges in development of ultrasensitive Home Brew assays: a case study using IL-13.
Bioanalysis;
11(11): 1045-1054, 2019 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31251105
15.
Development of an IL-6 point-of-care assay: utility for real-time monitoring and management of cytokine release syndrome and sepsis.
Bioanalysis;
11(19): 1777-1785, 2019 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31547696
16.
Establishment of neurofilament light chain Simoa assay in cerebrospinal fluid and blood.
Bioanalysis;
11(15): 1405-1418, 2019 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31401845
17.
Measurement of IL-17AA and IL-17FF as Pharmacodynamic Biomarkers to Demonstrate Target Engagement in the Phase I Study of MCAF5352A.
AAPS J;
21(1): 9, 2018 12 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30547287
18.
A Multi-site In-depth Evaluation of the Quanterix Simoa from a User's Perspective.
AAPS J;
20(1): 10, 2017 12 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29196830
19.
Commercial biomarker assays: friend and foe.
Bioanalysis;
8(22): 2351-2362, 2016 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27704870
20.
Characterization of IL-17AA and IL-17FF in rheumatoid arthritis and multiple sclerosis.
Bioanalysis;
8(22): 2317-2327, 2016 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27620302