Detalhe da pesquisa
1.
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection.
Cell;
184(8): 2167-2182.e22, 2021 04 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33811809
2.
Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors.
Cell;
179(4): 895-908.e21, 2019 10 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31675498
3.
Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases.
Proc Natl Acad Sci U S A;
119(9)2022 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35217625
4.
Semisynthesis of an evasin from tick saliva reveals a critical role of tyrosine sulfation for chemokine binding and inhibition.
Proc Natl Acad Sci U S A;
117(23): 12657-12664, 2020 06 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32461364
5.
Positive Allosteric Modulators of Metabotropic Glutamate Receptor 5 as Tool Compounds to Study Signaling Bias.
Mol Pharmacol;
99(5): 328-341, 2021 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33602724
6.
Phosphoproteomic characterization of the signaling network resulting from activation of the chemokine receptor CCR2.
J Biol Chem;
295(19): 6518-6531, 2020 05 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32241914
7.
Detailed In Vitro Pharmacological Characterization of Clinically Tested Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5.
Mol Pharmacol;
98(1): 49-60, 2020 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32358164
8.
Discovery of Potent Cyclic Sulfopeptide Chemokine Inhibitors via Reprogrammed Genetic Code mRNA Display.
J Am Chem Soc;
142(20): 9141-9146, 2020 05 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32330017
9.
Calcium-Sensing Receptor Internalization Is ß-Arrestin-Dependent and Modulated by Allosteric Ligands.
Mol Pharmacol;
96(4): 463-474, 2019 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31399503
10.
Investigating Internalization and Intracellular Trafficking of GPCRs: New Techniques and Real-Time Experimental Approaches.
Handb Exp Pharmacol;
245: 41-61, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29018878
11.
Rosiglitazone elicits in vitro relaxation in airways and precision cut lung slices from a mouse model of chronic allergic airways disease.
Am J Physiol Lung Cell Mol Physiol;
309(10): L1219-28, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26386117
12.
Variability in Human Bitter Taste Sensitivity to Chemically Diverse Compounds Can Be Accounted for by Differential TAS2R Activation.
Chem Senses;
40(6): 427-35, 2015 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25999325
13.
Bitter taste receptor agonists elicit G-protein-dependent negative inotropy in the murine heart.
FASEB J;
28(10): 4497-508, 2014 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25002118
14.
Cardiac human bitter taste receptors contain naturally occurring variants that alter function.
Biochem Pharmacol;
219: 115932, 2024 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37989413
15.
Unravelling G protein-coupled receptor signalling networks using global phosphoproteomics.
Br J Pharmacol;
2023 Feb 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36772927
16.
Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139.
Eur J Pharmacol;
943: 175553, 2023 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36736525
17.
Vascular cells improve functionality of human cardiac organoids.
Cell Rep;
42(5): 112322, 2023 05 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37105170
18.
Glycosylation Regulates N-Terminal Proteolysis and Activity of the Chemokine CCL14.
ACS Chem Biol;
16(6): 973-981, 2021 06 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33988967
19.
A Bitter Taste in Your Heart.
Front Physiol;
11: 431, 2020.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32457649
20.
Structural basis of chemokine and receptor interactions: Key regulators of leukocyte recruitment in inflammatory responses.
Protein Sci;
29(2): 420-432, 2020 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31605402