Detalhe da pesquisa
1.
Alzheimer's-Causing Mutations Shift Aß Length by Destabilizing γ-Secretase-Aßn Interactions.
Cell;
170(3): 443-456.e14, 2017 Jul 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28753424
2.
Alzheimer's-causing mutations shift Aß length by destabilizing γ-secretase-Aßn interactions.
Cell;
184(8): 2257-2258, 2021 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33861967
3.
Data-driven modelling of neurodegenerative disease progression: thinking outside the black box.
Nat Rev Neurosci;
25(2): 111-130, 2024 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38191721
4.
Two Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease.
N Engl J Med;
389(20): 1862-1876, 2023 Nov 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37966285
5.
Peripheral hearing loss at age 70 predicts brain atrophy and associated cognitive change.
J Neurol Neurosurg Psychiatry;
2024 Apr 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38569877
6.
Rates of cortical thinning in Alzheimer's disease signature regions associate with vascular burden but not with ß-amyloid status in cognitively normal adults at age 70.
J Neurol Neurosurg Psychiatry;
2024 Jan 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38199813
7.
Updating the study protocol: Insight 46 - a longitudinal neuroscience sub-study of the MRC National Survey of Health and Development - phases 2 and 3.
BMC Neurol;
24(1): 40, 2024 Jan 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38263061
8.
Clinical considerations in early-onset cerebral amyloid angiopathy.
Brain;
146(10): 3991-4014, 2023 10 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37280119
9.
Brain network decoupling with increased serum neurofilament and reduced cognitive function in Alzheimer's disease.
Brain;
146(7): 2928-2943, 2023 07 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36625756
10.
The presenilin 1 mutation P436S causes familial Alzheimer's disease with elevated Aß43 and atypical clinical manifestations.
Alzheimers Dement;
2024 Jun 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38824433
11.
Examining amyloid reduction as a surrogate endpoint through latent class analysis using clinical trial data for dominantly inherited Alzheimer's disease.
Alzheimers Dement;
20(4): 2698-2706, 2024 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38400532
12.
Presenilin-1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage.
Alzheimers Dement;
20(4): 2680-2697, 2024 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38380882
13.
Amyloid-Related Imaging Abnormalities in the DIAN-TU-001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease.
Ann Neurol;
92(5): 729-744, 2022 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36151869
14.
Aß profiles generated by Alzheimer's disease causing PSEN1 variants determine the pathogenicity of the mutation and predict age at disease onset.
Mol Psychiatry;
27(6): 2821-2832, 2022 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35365805
15.
Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology.
Brain;
145(10): 3594-3607, 2022 10 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35580594
16.
Acceptability and feasibility of plasma phosphorylated-tau181 in two memory services.
Int J Geriatr Psychiatry;
38(3): e5897, 2023 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36852663
17.
Biomarker clustering in autosomal dominant Alzheimer's disease.
Alzheimers Dement;
19(1): 274-284, 2023 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35362200
18.
Pattern and implications of neurological examination findings in autosomal dominant Alzheimer disease.
Alzheimers Dement;
19(2): 632-645, 2023 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35609137
19.
Association between carotid atherosclerosis and brain activation patterns during the Stroop task in older adults: An fNIRS investigation.
Neuroimage;
257: 119302, 2022 08 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35595200
20.
Amyloid processing in COVID-19-associated neurological syndromes.
J Neurochem;
161(2): 146-157, 2022 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35137414