Detalhe da pesquisa
1.
Improved pharmacokinetics and enhanced efficacy of the vancomycin derivative FU002 using a liposomal nanocarrier.
Nanomedicine;
56: 102731, 2024 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38158147
2.
Targeting Lewy body dementia with neflamapimod-rasagiline hybrids.
Arch Pharm (Weinheim);
357(6): e2300525, 2024 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38412454
3.
Nephrotoxicity of iopamidol is associated with mitochondrial impairment in human cell and teleost models.
Toxicol Appl Pharmacol;
466: 116493, 2023 05 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36977437
4.
Zebrafish (Danio rerio) larva as an in vivo vertebrate model to study renal function.
Am J Physiol Renal Physiol;
322(3): F280-F294, 2022 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35037468
5.
Altered protein expression of membrane transporters in isolated cerebral microvessels and brain cortex of a rat Alzheimer's disease model.
Neurobiol Dis;
169: 105741, 2022 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35472634
6.
Targeting Transporters for Drug Delivery to the Brain: Can We Do Better?
Pharm Res;
39(7): 1415-1455, 2022 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35359241
7.
Essential phospholipids decrease apoptosis and increase membrane transport in human hepatocyte cell lines.
Lipids Health Dis;
21(1): 91, 2022 Sep 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36153592
8.
Drug Delivery Strategies to Overcome the Blood-Brain Barrier (BBB).
Handb Exp Pharmacol;
273: 151-183, 2022.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33367937
9.
Extension of the Mechanistic Tissue Distribution Model of Rodgers and Rowland by Systematic Incorporation of Lysosomal Trapping: Impact on Unbound Partition Coefficient and Volume of Distribution Predictions in the Rat.
Drug Metab Dispos;
49(1): 53-61, 2021 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33148688
10.
Aryl hydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules.
Biol Chem;
400(10): 1335-1345, 2019 09 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30913027
11.
Quantitation of Lysosomal Trapping of Basic Lipophilic Compounds Using In Vitro Assays and In Silico Predictions Based on the Determination of the Full pH Profile of the Endo-/Lysosomal System in Rat Hepatocytes.
Drug Metab Dispos;
47(1): 49-57, 2019 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30409837
12.
Impact of Zn2+ on ABC Transporter Function in Intact Isolated Rat Brain Microvessels, Human Brain Capillary Endothelial Cells, and in Rat in Vivo.
Mol Pharm;
16(1): 305-317, 2019 01 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30422662
13.
The Bile Acid-Phospholipid Conjugate Ursodeoxycholyl-Lysophosphatidylethanolamide (UDCA-LPE) Disintegrates the Lipid Backbone of Raft Plasma Membrane Domains by the Removal of the Membrane Phospholipase A2.
Int J Mol Sci;
20(22)2019 Nov 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31717968
14.
In Vitro and In Situ Absorption and Metabolism of Sesquiterpenes from Petasites hybridus Extracts.
Planta Med;
84(11): 795-805, 2018 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29341029
15.
Zinc chloride rapidly stimulates efflux transporters in renal proximal tubules of killifish (Fundulus heteroclitus).
Toxicol Appl Pharmacol;
334: 88-99, 2017 11 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28882485
16.
Design and synthesis of a fluorinated quinazoline-based type-II Trk inhibitor as a scaffold for PET radiotracer development.
Bioorg Med Chem Lett;
27(12): 2771-2775, 2017 06 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28476569
17.
Engaging neuroscience to advance translational research in brain barrier biology.
Nat Rev Neurosci;
12(3): 169-82, 2011 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21331083
18.
Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier.
Pharm Res;
32(9): 2973-82, 2015 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25986174
19.
Genomic Knockout of Endogenous Canine P-Glycoprotein in Wild-Type, Human P-Glycoprotein and Human BCRP Transfected MDCKII Cell Lines by Zinc Finger Nucleases.
Pharm Res;
32(6): 2060-71, 2015 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25522789
20.
Current status in the therapy of liver diseases.
Int J Mol Sci;
15(5): 7500-12, 2014 Apr 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24786290