Detalhe da pesquisa
1.
Cardiomyocytes, cardiac endothelial cells and fibroblasts contribute to anthracycline-induced cardiac injury through RAS-homologous small GTPases RAC1 and CDC42.
Pharmacol Res;
203: 107165, 2024 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38561112
2.
Targeting Mechanisms of the DNA Damage Response (DDR) and DNA Repair by Natural Compounds to Improve cAT-Triggered Tumor Cell Death.
Molecules;
27(11)2022 Jun 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35684504
3.
Cisplatin-induced neurotoxicity involves the disruption of serotonergic neurotransmission.
Pharmacol Res;
174: 105921, 2021 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34601079
4.
Effects of Manganese on Genomic Integrity in the Multicellular Model Organism Caenorhabditis elegans.
Int J Mol Sci;
22(20)2021 Oct 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34681565
5.
Targeting the DNA damage response (DDR) by natural compounds.
Bioorg Med Chem;
28(4): 115279, 2020 02 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31980363
6.
In Vitro Assessment of the Genotoxic Hazard of Novel Hydroxamic Acid- and Benzamide-Type Histone Deacetylase Inhibitors (HDACi).
Int J Mol Sci;
21(13)2020 Jul 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32635356
7.
Hepatic Rac1 GTPase contributes to liver-mediated basal immune homeostasis and LPS-induced endotoxemia.
Biochim Biophys Acta Mol Cell Res;
1865(9): 1277-1292, 2018 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29932987
8.
Profiling of a suramin-derived compound library at recombinant human P2Y receptors identifies NF272 as a competitive but non-selective P2Y2 receptor antagonist.
Purinergic Signal;
15(3): 287-298, 2019 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31270713
9.
Rac1-mediated cardiac damage causes diastolic dysfunction in a mouse model of subacute doxorubicin-induced cardiotoxicity.
Arch Toxicol;
92(1): 441-453, 2018 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28710503
10.
Lovastatin protects keratinocytes from DNA damage-related pro-apoptotic stress responses stimulated by anticancer therapeutics.
Biochim Biophys Acta;
1863(6 Pt A): 1082-92, 2016 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26876155
11.
Integrin αvß3 expression in tongue squamous carcinoma cells Cal27 confers anticancer drug resistance through loss of pSrc(Y418).
Biochim Biophys Acta;
1863(8): 1969-78, 2016 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27108184
12.
Platinum-induced kidney damage: Unraveling the DNA damage response (DDR) of renal tubular epithelial and glomerular endothelial cells following platinum injury.
Biochim Biophys Acta;
1853(3): 685-98, 2015 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25565603
13.
Fatal Lymphoproliferative Disease in Two Siblings Lacking Functional FAAP24.
J Clin Immunol;
36(7): 684-92, 2016 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27473539
14.
Lovastatin prevents cisplatin-induced activation of pro-apoptotic DNA damage response (DDR) of renal tubular epithelial cells.
Toxicol Appl Pharmacol;
292: 103-14, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26739623
15.
Rac1 promotes diethylnitrosamine (DEN)-induced formation of liver tumors.
Carcinogenesis;
36(3): 378-89, 2015 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25556150
16.
Chronic heart damage following doxorubicin treatment is alleviated by lovastatin.
Pharmacol Res;
91: 47-56, 2015 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25462173
17.
DNA damage response (DDR) induced by topoisomerase II poisons requires nuclear function of the small GTPase Rac.
Biochim Biophys Acta;
1833(12): 3093-3103, 2013 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23999236
18.
Spongean alkaloids protect rat kidney cells against cisplatin-induced cytotoxicity.
Anticancer Drugs;
25(8): 917-29, 2014 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24820908
19.
Cisplatin-induced DNA crosslinks trigger neurotoxicity in C. elegans.
Biochim Biophys Acta Mol Cell Res;
1871(1): 119591, 2024 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37730131
20.
Novel meriolin derivatives potently inhibit cell cycle progression and transcription in leukemia and lymphoma cells via inhibition of cyclin-dependent kinases (CDKs).
Cell Death Discov;
10(1): 279, 2024 Jun 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38862521