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1.
Head Neck Surg ; 10(5): 344-5, 1988.
Artigo em Inglês | MEDLINE | ID: mdl-3220775

RESUMO

An unusual complication of radical neck dissection is presented. Necrosis of the anterior half of the tongue developed gradually within the first week of bilateral neck dissection. The patient had previously received radiotherapy.


Assuntos
Esvaziamento Cervical , Complicações Pós-Operatórias , Língua/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Necrose
2.
Photochem Photobiol ; 70(3): 348-52, 1999 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-10483363

RESUMO

Human skin biopsies (hair-bearing scalp skin and non-hair-bearing breast skin) were treated with t-butylhydroperoxide, irradiated with UV light (UVR) or irradiated with 694 nm ruby laser red light. Free-radical production and oxidative stress were assessed with electron spin resonance spectroscopy (ESR) using the ascorbate radical as a marker. In comparison with both UVR and t-butyl-hydroperoxide (which readily induce the ascorbate radical in hair-bearing and hairless skin), 694 nm red light does not result in the formation of the ascorbate radical in detectable concentrations. Spin-trapping experiments with the spin trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO) showed that while free radicals could be detected after treatment of skin with t-butylhydroperoxide, radicals could not be trapped after laser treatment. Treatment of lasered skin (containing DMPO) with t-butylhydroperoxide produced radical adducts as well as the ascorbate radical, demonstrating that the laser neither depletes endogenous ascorbate nor the preadministered spin trap. It is concluded that 694 nm red light does not induce oxidative stress in human skin in levels comparable either to t-butyl hydroperoxide or UV light.


Assuntos
Remoção de Cabelo/efeitos adversos , Lasers/efeitos adversos , Estresse Oxidativo , Pele/metabolismo , Pele/efeitos da radiação , Óxidos N-Cíclicos , Espectroscopia de Ressonância de Spin Eletrônica , Radicais Livres/metabolismo , Humanos , Marcadores de Spin , Detecção de Spin , Raios Ultravioleta , terc-Butil Hidroperóxido/metabolismo , terc-Butil Hidroperóxido/toxicidade
3.
Eur J Cardiothorac Surg ; 4(1): 48-50, 1990.
Artigo em Inglês | MEDLINE | ID: mdl-2137708

RESUMO

Three babies who developed infection in their median sternotomy wounds are reported. In one child, a retrosternal abscess was drained and in the other two cases, the wounds dehisced. The wound cavities were filled with a rectus abdominis myocutaneous island flap and in each case, the wounds healed primarily. Early flap repair resolved the infection, shortened the hospital stay and provided protection to the exposed mediastinum.


Assuntos
Esterno/cirurgia , Infecção da Ferida Cirúrgica/cirurgia , Músculos Abdominais/cirurgia , Procedimentos Cirúrgicos Cardíacos , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Retalhos Cirúrgicos
4.
Plast Reconstr Surg ; 81(4): 545-9, 1988 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-3347664

RESUMO

Traditional silicone prostheses have been found to be inflexible, heavy, and of poor color match when used on the limbs. Ten patients distressed by contour deformities on their limbs after the wide excision of malignancies or following trauma were fitted with a light-weight prosthesis whose special features include a flexible foam backing, an outer tinted skin, and finely feathered edges that draw the eye away from the margins of the defect. The prosthesis sticks dependably to the skin and is particularly effective when worn under stockings or tights. When reviewed, all patients were continuing to use the device. It is a useful alternative to surgical reconstruction in such patients.


Assuntos
Cicatriz/patologia , Próteses e Implantes , Adulto , Idoso , Comportamento do Consumidor , Feminino , Humanos , Pessoa de Meia-Idade , Desenho de Prótese , Silicones
5.
Plast Reconstr Surg ; 102(7): 2325-32; discussion 2333-5, 1998 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-9858166

RESUMO

Despite the multitude of corrective procedures described, adequate surgical correction of the congenital constricted ear remains a challenge. The maintenance of the shape and elevation of the reconstructed upper neohelix poses a particular problem. In the present series, experiences with lop ear correction utilizing standard techniques and the use of the mastoid hitch as a useful adjunct to these procedures are described. A total of 19 ears were reconstructed. There were three type 1, eight type 2a, seven type 2b, and one type 3 deformities (Tanzer classification). A graded sequence of procedures was adopted. Mild deformities were corrected by cartilage scoring techniques; a V-Y advancement of the helical root was added for moderate deformities. Cartilage expansion by a banner flap was required for more severe deformities. A mastoid hitch, whereby the refashioned upper neohelix is sutured to the mastoid fascia, should be used as an adjunct to these procedures to maintain helical elevation and prevent recurrence. Severe type 3 deformities may require autologous auricular reconstruction. Mean follow-up time was 1 year. There were six excellent, seven good, four fair, and two poor results. Two patients who had not had mastoid hitch procedures developed a recurrence of the lop deformity. Adequate surgical correction of constricted ear deformities requires a variety of surgical techniques. The mastoid hitch being used for constricted ear correction has not been described elsewhere. The mastoid hitch is a useful adjunctive procedure that may be used effectively in combination with other procedures.


Assuntos
Orelha Externa/anormalidades , Orelha Externa/cirurgia , Adolescente , Criança , Pré-Escolar , Feminino , Seguimentos , Humanos , Masculino , Procedimentos de Cirurgia Plástica/métodos
6.
Plast Reconstr Surg ; 108(6): 1487-90; discussion 1491, 2001 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-11711914

RESUMO

Anterior riberation methods of otoplasty have been criticized because of the risk of anterior hematoma that can cause anterior skin necrosis, scarring, and even cartilage destruction caused by infection. As a result, cartilage-sparing otoplasty such as the Mustardé and Furnas types has been increasingly popular. However, postauricular suture extrusion may result, and recurrence rates of up to 25 percent have been recorded. In this study, cartilage-sparing otoplasty is refined by the addition of a postauricular fascial flap to reduce suture extrusion and recurrence rates. Fifty-one patients underwent otoplasty (45 bilateral, six unilateral). This technique involves the elevation of a fascial flap from the postauricular region. A new antihelical fold is then created by Mustardé sutures, and the conchal bowl is rotated by Furnas-type concha-mastoid sutures. The fascial flap is then advanced to cover the sutures with a supplementary vascularized layer to prevent suture extrusion. In addition, the advancement of the flap acts as a postauricular support to prevent recurrence. A natural-looking antihelical fold and helical rim is created by this technique. There were no hematomas. There was recurrence in eight ears (8 percent) in six patients. Two patients requested further surgery. No patients developed suture extrusion or granuloma. This is a simple and intrinsically safe procedure and does not cause irreparable complications such as anterior scarring or skin necrosis. The postauricular fascial flap seems to prevent suture extrusion. It may also help to reduce recurrence rates to acceptable levels.


Assuntos
Orelha Externa/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Retalhos Cirúrgicos , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Cartilagem da Orelha/cirurgia , Orelha Externa/anormalidades , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias
7.
Plast Reconstr Surg ; 90(3): 377-81, 1992 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-1513883

RESUMO

Intracranial volume and intracranial pressure have been measured in 66 children with craniosynostosis, 48 boys and 18 girls. The premature fusion of skull sutures is assumed to restrict skull growth and predispose to elevated intracranial pressure. Thirteen children (20 percent) had raised intracranial pressure and demonstrated a significant restriction of skull growth. In this series, volume measurement alone, however, did not serve as a reliable predictor that the intracranial pressure was raised.


Assuntos
Encéfalo/patologia , Craniossinostoses/patologia , Craniossinostoses/fisiopatologia , Pressão Intracraniana , Crânio/patologia , Adolescente , Encéfalo/diagnóstico por imagem , Criança , Pré-Escolar , Suturas Cranianas/patologia , Craniossinostoses/classificação , Feminino , Humanos , Lactente , Pressão Intracraniana/fisiologia , Masculino , Pseudotumor Cerebral/fisiopatologia , Crânio/diagnóstico por imagem , Tomografia Computadorizada por Raios X
8.
Plast Reconstr Surg ; 103(6): 1736-43, 1999 May.
Artigo em Inglês | MEDLINE | ID: mdl-10323715

RESUMO

Ruby laser-assisted hair removal is thought to work via selective photothermolysis, which relies on light reaching the deeper layers of skin, and the absorption of light by the target chromophore, melanin. It is therefore possible that efficacy of treatment is affected by anatomic factors that determine the amount of light reaching the hair bulbs (i.e., skin color, depth of intracutaneous hair, epidermal thickness and dermal density) and the melanin content of hair. To examine this hypothesis, a prospective study was performed. Forty-eight volunteers were treated with the Chromos 694 Depilation Ruby Laser at a single standard fluence of 11 J/cm2. Treatment efficacy was determined by measuring hair density at 3 and 7 months after treatment. Epidermal depth and dermal density were measured from 2-mm biopsies taken before treatment, and the intracutaneous hair length was determined from plucked hair. Skin color was assessed using a spectrophotometer, and melanin content of dissolved hair was assessed using spectrophotometry. Efficacy of treatment for each patient was compared with the patient's age, intracutaneous hair length, epidermal depth, dermal density, skin color, and total melanin content and relative eumelanin content of hair. No correlation was found between the efficacy of treatment and age and the various anatomic factors. Patients with higher eumelanin content in their hair had better long-term results (Spearman rank test, p = 0.00219). The results suggested that the efficacy of treatment did not depend solely on the amount of laser light penetrating the skin but correlated well with the eumelanin content of hair. The clinical implication of this finding is discussed.


Assuntos
Folículo Piloso/química , Remoção de Cabelo/métodos , Lasers , Melaninas/análise , Pele/anatomia & histologia , Adolescente , Adulto , Idoso , Estudos de Avaliação como Assunto , Feminino , Humanos , Pessoa de Meia-Idade , Estudos Prospectivos
9.
Tumori ; 86(4): 289-92, 2000.
Artigo em Inglês | MEDLINE | ID: mdl-11016706

RESUMO

Vinorelbine tartrate (Navelbine, Burroughs Wellcome Company, Research Triangle Park, NC, USA) is a semisynthetic vinca alkaloid approved in many countries for the first-line treatment of patients with advanced non-small-cell lung cancer. It is also used in the treatment of advanced breast and ovarian cancers and lymphoma. Like other vinca alkaloids, Navelbine can cause skin necrosis as a consequence of inadvertent extravasation in surrounding tissues during intravenous administration. In such cases, early treatment is strongly advocated. There is no documented case of vinorelbine extravasation in the literature. The authors herein report two cases successfully treated with hyaluronidase injections plus saline flushout under local anesthesia.


Assuntos
Antineoplásicos Fitogênicos/efeitos adversos , Traumatismos da Mão/tratamento farmacológico , Hialuronoglucosaminidase/uso terapêutico , Vimblastina/análogos & derivados , Vimblastina/efeitos adversos , Anestesia Local , Antineoplásicos Fitogênicos/administração & dosagem , Extravasamento de Materiais Terapêuticos e Diagnósticos , Feminino , Humanos , Hialuronoglucosaminidase/administração & dosagem , Pessoa de Meia-Idade , Cloreto de Sódio/uso terapêutico , Resultado do Tratamento , Vimblastina/administração & dosagem , Vinorelbina
10.
J Hand Surg Br ; 12(2): 182-4, 1987 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-3624972

RESUMO

67 patients with 176 repaired flexor tendons have been reviewed after a mean follow-up interval of 26.4 months. After repair, mean grip strength was 74.5%, mean finger flexion pressure 76.8% and mean finger pinch pressure 74.7% of that of the opposite uninjured hand or digit. For 16 patients with repaired flexor pollicis longus tendons, mean key pinch was 78.7%. Grip strength was reduced after injury to tendons alone, but was especially reduced when there was concomitant damage to the median or ulnar nerves.


Assuntos
Traumatismos dos Dedos/fisiopatologia , Traumatismos dos Tendões/fisiopatologia , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Feminino , Traumatismos dos Dedos/cirurgia , Dedos/fisiopatologia , Seguimentos , Mãos/fisiopatologia , Humanos , Masculino , Movimento , Pressão , Traumatismos dos Tendões/cirurgia
11.
J Hand Surg Br ; 12(3): 321-5, 1987 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-3437197

RESUMO

67 patients with 176 repaired flexor tendons have been reviewed after a mean interval of 26.4 months. 160 tendons to 100 fingers, and 16 flexor pollicis longus tendons were repaired. When evaluated by Buck-Gramcko criteria, the functional results in 92% of the fingers and 69% of the thumbs were graded as excellent or good. Patients with partially divided tendons fared no better than those whose tendons were completely divided. The results of repair in the little finger were less satisfactory than in other fingers.


Assuntos
Traumatismos dos Dedos/cirurgia , Traumatismos da Mão/cirurgia , Traumatismos dos Tendões/cirurgia , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias , Polegar
12.
J Hand Surg Br ; 13(1): 62-5, 1988 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-3361209

RESUMO

This is a report of five patients who sustained untidy division of flexor tendons in zones 1 and 2, associated with overlying soft tissue loss. Contrary to traditional teaching, the tendon injuries were repaired primarily, and the tissue loss was made good with a cross-finger flap. At final evaluation, three cases were assigned excellent grades and two cases fair grades by Kleinert criteria. This unexpectedly favourable outcome may be due to a quality of the inner surface of the cross-finger flap and/or to staggering of the skin and tendon suture lines.


Assuntos
Traumatismos dos Dedos/cirurgia , Retalhos Cirúrgicos , Traumatismos dos Tendões/cirurgia , Adolescente , Adulto , Feminino , Traumatismos dos Dedos/reabilitação , Humanos , Masculino , Métodos , Pessoa de Meia-Idade
16.
J Plast Reconstr Aesthet Surg ; 59(12): 1446-9, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-17113539

RESUMO

Prominent ear correction is a common operation. Complication as a result of infection has been quoted at between 3% and 5% [Calder JC, Nasaan A. Morbidity of otoplasty: a review of 562 consecutive cases. Br J Plast Surg 1994;47:170-4 and Jeffery SLA. Complications following correction of prominent ears: an audit review of 122 cases. Br J Plast Surg 1999;52:588-90.]. We present two cases referred for ear reconstruction following catastrophic post-operative infection at the time of pinnaplasty, leaving each patient with significant helical rim deformities. Both patients displayed evidence of active post-auricular eczema at the time of their primary surgery. Dermatological research has highlighted the increased colonisation of Staphylococcus aureus in particular within areas of atopic eczema in comparison to normal skin. We advise delaying ear surgery in the presence of a rash in view of the potentially devastating complications that may result. This approach may be extended to all cutaneous surgery where treatment of the rash is advocated prior to embarking on an elective surgical procedure.


Assuntos
Orelha Externa/anormalidades , Orelha Externa/cirurgia , Eczema/complicações , Procedimentos de Cirurgia Plástica , Infecção da Ferida Cirúrgica/etiologia , Adolescente , Criança , Contraindicações , Deformidades Adquiridas da Orelha/etiologia , Deformidades Adquiridas da Orelha/cirurgia , Feminino , Humanos , Infecção da Ferida Cirúrgica/prevenção & controle
17.
Br J Plast Surg ; 46(2): 91-6, 1993 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-8461914

RESUMO

The leakage of cytotoxic drugs, intravenous nutrition, solutions of calcium, potassium, bicarbonate and even 10% dextrose outside the vein into which they are delivered is known not only to cause skin necrosis but also to precipitate significant scarring around tendons, nerves and joints. In this review of 96 patients with extravasation injuries seen between 1987 and 1992 at St Thomas' Hospital, Mount Vernon Hospital and The Hospital for Sick Children, Great Ormond Street, several patients required extensive reconstruction and in some, despite this, extravasation injury has rendered a limb virtually useless. Two techniques, liposuction and saline flushout, are described to remove extravasated material while conserving the overlying skin. Analysis of flushout material confirmed that the extravasated material was actually being removed. Forty four of the study group in whom noxious materials were known to have extravasated underwent such early treatment. The results in this group were quite striking--the majority (86%) healed without any soft tissue loss at all. The early referral and treatment of extravasation injuries is, therefore, recommended.


Assuntos
Extravasamento de Materiais Terapêuticos e Diagnósticos/complicações , Irrigação Terapêutica , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Contratura/prevenção & controle , Feminino , Humanos , Lactente , Recém-Nascido , Lipectomia , Masculino , Pessoa de Meia-Idade , Necrose , Pele/patologia , Cloreto de Sódio/administração & dosagem , Retalhos Cirúrgicos , Fatores de Tempo
18.
Br J Plast Surg ; 47(8): 573-4, 1994 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-7697287

RESUMO

Non-hypoplastic congenital ear deformities are amenable to non-surgical treatment with splinting in the neonatal period. It is therefore important to determine when the deformity occurs. 100 postal questionnaires were sent to parents to study, retrospectively, the evolution of the prominent ear deformity in their children. 79 questionnaires were returned. As remembered by parents, the deformity was first noted at birth in 48 (61%) children, in 68 (86%) by 6 months and in all cases by 5 years. Therefore a large number of patients with prominent ears could be treated effectively, non surgically, early in life, without anaesthetic and with minimal cost.


Assuntos
Cartilagem da Orelha/anormalidades , Cartilagem da Orelha/crescimento & desenvolvimento , Contenções , Adolescente , Fatores Etários , Criança , Pré-Escolar , Cartilagem da Orelha/embriologia , Feminino , Humanos , Masculino , Estudos Retrospectivos , Inquéritos e Questionários
19.
Burns Incl Therm Inj ; 13(2): 131-5, 1987 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-3580936

RESUMO

Twenty-six patients who sustained significant burn injuries as a result of striking underground electric cables are reviewed. This study sets out to highlight why such injuries occur and to recommend preventive measures to those digging in the London area. There were three deaths in this series.


Assuntos
Acidentes de Trabalho , Queimaduras por Corrente Elétrica/epidemiologia , Acidentes de Trabalho/prevenção & controle , Adolescente , Adulto , Queimaduras por Corrente Elétrica/prevenção & controle , Queimaduras por Corrente Elétrica/terapia , Inglaterra , Humanos , Masculino , Pessoa de Meia-Idade
20.
Br J Plast Surg ; 39(4): 505-9, 1986 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-3779197

RESUMO

The long term results of flap cover in 28 cases of exposed metalwork are presented. The patients fall into two groups; those with exposure of plates after internal fixation of fractures (14), and those with exposed knee or elbow prosthetic joints (14). The average duration of metal exposure at the time of referral was 6.4 weeks. In the majority of cases, cover was achieved by local muscle or fasciocutaneous flaps. The average duration of follow-up was 20 months. Metalwork was covered and preserved in 16 cases (57%). The remainder had persistent discharging sinuses or overt sepsis despite survival of the overlying flap. The results of this series are discussed in relation to the pre-operative microflora and the duration of metal exposure.


Assuntos
Fixação Interna de Fraturas , Prótese Articular , Retalhos Cirúrgicos , Adolescente , Adulto , Idoso , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Prognóstico , Infecção dos Ferimentos/microbiologia
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