Detalhe da pesquisa
1.
7-Dehydrocholesterol is an endogenous suppressor of ferroptosis.
Nature;
626(7998): 401-410, 2024 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38297129
2.
Metabolic Control of Sensory Neuron Survival by the p75 Neurotrophin Receptor in Schwann Cells.
J Neurosci;
41(42): 8710-8724, 2021 10 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34507952
3.
Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain.
J Lipid Res;
63(8): 100249, 2022 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35839864
4.
Ferroptosis: A Promising Therapeutic Target for Neonatal Hypoxic-Ischemic Brain Injury.
Int J Mol Sci;
23(13)2022 Jul 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35806425
5.
Maternal cariprazine exposure inhibits embryonic and postnatal brain cholesterol biosynthesis.
Mol Psychiatry;
25(11): 2685-2694, 2020 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32504050
6.
Maternal aripiprazole exposure interacts with 7-dehydrocholesterol reductase mutations and alters embryonic neurodevelopment.
Mol Psychiatry;
24(4): 491-500, 2019 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30742019
7.
Desmosterolosis and desmosterol homeostasis in the developing mouse brain.
J Inherit Metab Dis;
42(5): 934-943, 2019 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30891795
8.
Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis.
Toxicol Appl Pharmacol;
349: 21-28, 2018 06 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29698737
9.
Vulnerability of DHCR7+/- mutation carriers to aripiprazole and trazodone exposure.
J Lipid Res;
58(11): 2139-2146, 2017 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28972118
10.
Cytochrome c reacts with cholesterol hydroperoxides to produce lipid- and protein-derived radicals.
Biochemistry;
54(18): 2841-50, 2015 May 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25865416
11.
Assay of protein and peptide adducts of cholesterol ozonolysis products by hydrophobic and click enrichment methods.
Chem Res Toxicol;
27(10): 1757-68, 2014 Oct 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25185119
12.
Enhancing 7-dehydrocholesterol suppresses brain ferroptosis and tissue injury after neonatal hypoxia-ischemia.
Sci Rep;
14(1): 7924, 2024 04 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38575644
13.
Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome.
J Lipid Res;
54(10): 2842-50, 2013 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23828810
14.
Covalent binding and anchoring of cytochrome c to mitochondrial mimetic membranes promoted by cholesterol carboxyaldehyde.
Chem Res Toxicol;
26(10): 1536-44, 2013 Oct 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24059586
15.
Identifying Molecular Fragments That Drive 7-Dehydrocholesterol Elevation.
ACS Pharmacol Transl Sci;
5(1): 3-7, 2022 Jan 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35059566
16.
Neonatal Hypoxic-Ischemic Brain Injury Alters Brain Acylcarnitine Levels in a Mouse Model.
Metabolites;
12(5)2022 May 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35629971
17.
Dose-Response Effects of 7-Dehydrocholesterol Reductase Inhibitors on Sterol Profiles and Vesicular Stomatitis Virus Replication.
ACS Pharmacol Transl Sci;
5(11): 1086-1096, 2022 Nov 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36407960
18.
Ubiquitous Aberration in Cholesterol Metabolism across Pancreatic Ductal Adenocarcinoma.
Metabolites;
12(1)2022 Jan 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35050168
19.
Altered Cholesterol Biosynthesis Affects Drug Metabolism.
ACS Omega;
6(8): 5490-5498, 2021 Mar 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33681590
20.
Interaction of maternal immune activation and genetic interneuronal inhibition.
Brain Res;
1759: 147370, 2021 05 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33600830