Detalhe da pesquisa
1.
Assessment of the predictive capacity of the 3T3 Neutral Red Uptake cytotoxicity test method to identify substances not classified for acute oral toxicity (LD50>2000 mg/kg): results of an ECVAM validation study.
Regul Toxicol Pharmacol;
65(3): 344-65, 2013 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23246604
2.
A selective, non-peptide caspase-1 inhibitor, VRT-018858, markedly reduces brain damage induced by transient ischemia in the rat.
Neuropharmacology;
53(5): 638-42, 2007 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17845807
3.
The role of inflammation in CNS injury and disease.
Br J Pharmacol;
147 Suppl 1: S232-40, 2006 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16402109
4.
Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia.
J Neurosci;
23(16): 6470-4, 2003 Jul 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12878687
5.
Metabolic activity: a novel indicator of neuronal survival in the murine dopaminergic cell line CAD.
J Mol Neurosci;
27(1): 65-77, 2005.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16055947
6.
Involvement of caspases and calpains in cerebrocortical neuronal cell death is stimulus-dependent.
Br J Pharmacol;
135(4): 1069-77, 2002 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11861336
7.
CNS injury: the role of the cytokine IL-1.
Vet J;
168(3): 230-7, 2004 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15501140
8.
Exposure-driven risk assessment: applying exposure-based waiving of toxicity tests under REACH.
Food Chem Toxicol;
49(8): 1661-73, 2011 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21458516
9.
Integrin-binding RGD peptides induce rapid intracellular calcium increases and MAPK signaling in cortical neurons.
Mol Cell Neurosci;
34(2): 147-54, 2007 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17150373
10.
Insulin-like growth factor-1-dependent maintenance of neuronal metabolism through the phosphatidylinositol 3-kinase-Akt pathway is inhibited by C2-ceramide in CAD cells.
Eur J Neurosci;
25(10): 3030-8, 2007 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17561816
11.
Interleukin-1-induced neurotoxicity is mediated by glia and requires caspase activation and free radical release.
J Neurochem;
98(1): 258-66, 2006 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16805812
12.
Activation of integrin alpha5beta1 delays apoptosis of Ntera2 neuronal cells.
Mol Cell Neurosci;
28(3): 588-98, 2005 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15737747
13.
Neuroprotective effects of the synthetic cannabinoid HU-210 in primary cortical neurons are mediated by phosphatidylinositol 3-kinase/AKT signaling.
Mol Cell Neurosci;
28(1): 189-94, 2005 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15607953