The influence of exercise on albumin excretion rate in borderline hypertensives and in offspring of hypertensive parents.

We investigated exercise induced urinary albumin excretion rate (UAE)(ex-UAE) in patients with borderline hypertension (BH) compared to normotensives with positive-PFH and negative-NFH family history of hypertension. The study population consisted of 20 young, non-obese males with BH defined according to WHO criteria and confirmed by 24 h ambulatory blood pressure (ABP) and 40 healthy matched normotensives (PFH = 20 and NFH = 20). Twenty-four hour UAE was assessed by day and night time urine collection. BH and normotensive subjects performed a 20 min ergometric graded exercise test. The relationship between 24 h UAE, 24 h ABP and 2-D-echocardiographic left ventricular mass index (LVMI) were examined. The three groups did not differ in 24 h UAE. Exercise induced a significant increase in UAE only in BH. Exercise induced UAE was greater in BH compared to normotensives: BH = 54.3(21-125), PFH = 37.6(13-62), NFH = 9.7(0-35)micrograms/min, data expressed as median (I quartile-III quartile). Pooled data from all three groups showed a positive correlation between ex-UAE and systolic BP (SBP) during night time (by multiple regression analysis). In conclusion, BH without other known cardiovascular risk factors, moderate dynamic exercise induced an excessive increase in UAE.

[Arterial hypertension caused by abnormality and translocation of the kidney]. / Nadcisnienie tetnicze w wyniku zaburzen rozwoju i przemieszczenia nerki.

The authors described developmental anomaly of the right kidney associated with hypertension and pyonephrosis in a 37 years old male. The authors reported the diagnostic problems in this kind of hypertension. After nephrectomy had been performed the elevated blood pressure returned to normal values without any additional pharmacological treatment.

[Bacterial endocarditis in patients treated with maintenance hemodialysis]. / Bakteryjne zapalenie wsierdzia u pacjentów leczonych przewlekla hemodializa.

UNLABELLED: Bacterial endocarditis (BE) is one of the most severe complications of hemodialysis (HD). The aim of the study was to analyse frequency and severity of BE in patients treated with HD in our dialysis unit. During the period 1969-1993276 patients were treated with HD in Gdansk. In 23 cases (9F, 14M) HD treatment was complicated with BE. Patients were divided into two groups on basis of diagnostic criteria: I-13 patients (5F,8M) with BE diagnosed by means of clinical picture and positive blood culture.; II-10 (4F, 10M) with diagnosis additionally confirmed by echocardiography. In patients from group I BE was observed more often during the first 2 years of HD. In group II during 3-5 years of dialysis therapy, gram negative microorganisms were the most frequent etiological factors. The mean period of antibiotic therapy was 35 days. In all patients from group II changes in the bicuspid valve, in 60% of them additionally in aortic valve and in one patient also in the tricuspid valve were observed. In five patients changes in the parietal endocardium were also present. Development of organic valvular changes was observed in nine patients. Seven of 22 patients died during the acute phase of BE and two others from complications connected with BE. The longest survival of patients after BE was over 10 years. CONCLUSIONS: 1. The threat of BE in patients treated with HD decreased between 1987 and 1993 in comparison with the initial period of our HD station operations.(ABSTRACT TRUNCATED AT 250 WORDS)

[Recurrent pulmonary embolism in an athlete. Vena cava filter implantation as a effective alternative to medical treatment]. / Nawracajaca zatorowosc plucna u sportowca. Implantacja filtru do zyly glównej dolnej jako skuteczna alternatywa leczenia zachowawczego.

The case of 63 years old judo trainer, actively working and suffering from pulmonary embolism originating from deep vein thrombosis aggravated by sport traumas, is presented. Repeated episodes of pulmonary embolism, despite treatment with oral anticoagulants, have led to alternative method of treatment--vena cava filter insertion. Diagnosis achieving process, concerning the sportive lifestyle, and the effectiveness of pharmacological treatment, are discussed.