Detalhe da pesquisa
1.
Structure of 3'-PO4/5'-OH RNA ligase RtcB in complex with a 5'-OH oligonucleotide.
RNA;
2021 Feb 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33619169
2.
Structure and mechanism of Mycobacterium smegmatis polynucleotide phosphorylase.
RNA;
2021 Jun 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34088850
3.
Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res;
48(10): 5603-5615, 2020 06 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32315072
4.
Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme.
Nucleic Acids Res;
48(6): 3165-3180, 2020 04 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32034423
5.
Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor.
Nucleic Acids Res;
47(22): 11826-11838, 2019 12 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31722405
6.
Structure and two-metal mechanism of fungal tRNA ligase.
Nucleic Acids Res;
47(3): 1428-1439, 2019 02 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30590734
7.
Activity and structure of Pseudomonas putida MPE, a manganese-dependent single-strand DNA endonuclease encoded in a nucleic acid repair gene cluster.
J Biol Chem;
294(19): 7931-7941, 2019 05 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30894417
8.
Structures of ATP-bound DNA ligase D in a closed domain conformation reveal a network of amino acid and metal contacts to the ATP phosphates.
J Biol Chem;
294(13): 5094-5104, 2019 03 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30718283
9.
Distinctive structural basis for DNA recognition by the fission yeast Zn2Cys6 transcription factor Pho7 and its role in phosphate homeostasis.
Nucleic Acids Res;
46(21): 11262-11273, 2018 11 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30212894
10.
Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
Nucleic Acids Res;
46(8): 4164-4175, 2018 05 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29635474
11.
Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD+-dependent polynucleotide ligases.
Proc Natl Acad Sci U S A;
114(10): 2592-2597, 2017 03 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28223499
12.
Structural basis for the GTP specificity of the RNA kinase domain of fungal tRNA ligase.
Nucleic Acids Res;
45(22): 12945-12953, 2017 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29165709
13.
Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast.
RNA;
22(7): 1011-25, 2016 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27165520
14.
Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase.
Proc Natl Acad Sci U S A;
112(45): 13868-73, 2015 Nov 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26512110
15.
Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia.
PLoS Genet;
11(6): e1005262, 2015 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26102509
16.
KIR3DS1-Specific D0 Domain Polymorphisms Disrupt KIR3DL1 Surface Expression and HLA Binding.
J Immunol;
195(3): 1242-50, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26109640
17.
Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3.
J Biol Chem;
290(50): 30018-29, 2015 Dec 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26487718
18.
Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.
Proc Natl Acad Sci U S A;
110(36): 14634-9, 2013 Sep 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23959867
19.
Structural basis for angiopoietin-1-mediated signaling initiation.
Proc Natl Acad Sci U S A;
110(18): 7205-10, 2013 Apr 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23592718
20.
A structural view of the dissociation of Escherichia coli tryptophanase.
Acta Crystallogr D Biol Crystallogr;
71(Pt 12): 2364-71, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26627645