Detalhe da pesquisa
1.
Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout.
J Am Chem Soc;
144(41): 18861-18875, 2022 10 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36200994
2.
First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement.
Chembiochem;
23(14): e202200180, 2022 07 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35608330
3.
Inclusion Complexes of Gold(I)-Dithiocarbamates with ß-Cyclodextrin: A Journey from Drug Repurposing towards Drug Discovery.
Chemistry;
27(47): 12156-12165, 2021 Aug 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34114261
4.
Constitutional PIGA mutations cause a novel subtype of hemochromatosis in patients with neurologic dysfunction.
Blood;
139(9): 1418-1422, 2022 03 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34875027
5.
The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines.
Arch Toxicol;
92(8): 2649-2664, 2018 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29947893
6.
Parametric modeling and optimal experimental designs for estimating isobolograms for drug interactions in toxicology.
J Biopharm Stat;
28(4): 763-777, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29173022
7.
Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease.
Am J Respir Crit Care Med;
191(8): 902-13, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25607238
8.
Impaired aldehyde dehydrogenase 1 subfamily member 2A-dependent retinoic acid signaling is related with a mesenchymal-like phenotype and an unfavorable prognosis of head and neck squamous cell carcinoma.
Mol Cancer;
14: 204, 2015 Dec 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26634247
9.
Low level of antioxidant capacity biomarkers but not target overexpression predicts vulnerability to ROS-inducing drugs.
Redox Biol;
62: 102639, 2023 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36958250
10.
Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors.
ChemMedChem;
15(13): 1163-1174, 2020 07 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32348628
11.
Synthesis and Structure-Activity Relationships of N-(4-Benzamidino)-Oxazolidinones: Potent and Selective Inhibitors of Kallikrein-Related Peptidase 6.
ChemMedChem;
15(1): 79-95, 2020 01 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31675166
12.
Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated.
J Med Chem;
62(9): 4426-4443, 2019 05 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30964290
13.
Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance.
Sci Rep;
8(1): 10039, 2018 07 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29968769
14.
Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity.
J Med Chem;
61(19): 8859-8874, 2018 10 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30212625
15.
The response of Mannheimia haemolytica to iron limitation: implications for the acquisition of iron in the bovine lung.
Vet Microbiol;
121(3-4): 316-29, 2007 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17240088
16.
Real-world evidence for preventive effects of statins on cancer incidence: A trans-Atlantic analysis.
Clin Transl Med;
12(2): e726, 2022 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35184411
17.
Identification and characterisation of the dopamine receptor II from the cat flea Ctenocephalides felis (CfDopRII).
Insect Biochem Mol Biol;
36(10): 749-58, 2006 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17027841
18.
Spiroepoxytriazoles Are Fumagillin-like Irreversible Inhibitors of MetAP2 with Potent Cellular Activity.
ACS Chem Biol;
11(4): 1001-11, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26686773
19.
Microarray analysis of Haemophilus parasuis gene expression under in vitro growth conditions mimicking the in vivo environment.
Vet Microbiol;
110(3-4): 255-63, 2005 Oct 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16144750