Detalhe da pesquisa
1.
In vitro susceptibility of Neisseria gonorrhoeae to netilmicin and etimicin in comparison to gentamicin and other aminoglycosides.
Eur J Clin Microbiol Infect Dis;
43(5): 821-828, 2024 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38388739
2.
Optimization of the antimicrobial peptide Bac7 by deep mutational scanning.
BMC Biol;
20(1): 114, 2022 05 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35578204
3.
Short Synthesis of (+)-Actinobolin: Simple Entry to Complex Small-Molecule Inhibitors of Protein Synthesis.
Angew Chem Int Ed Engl;
61(17): e202116520, 2022 04 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35167723
4.
Antimicrobial susceptibility patterns of respiratory Gram-negative bacterial isolates from COVID-19 patients in Switzerland.
Ann Clin Microbiol Antimicrob;
20(1): 64, 2021 Sep 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34493302
5.
Apralogs: Apramycin 5-O-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resistance Determinant.
J Am Chem Soc;
142(1): 530-544, 2020 01 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31790244
6.
Predictive Analysis of the Side Chain Conformation of the Higher Carbon Sugars: Application to the Preorganization of the Aminoglycoside Ring 1 Side Chain for Binding to the Bacterial Ribosomal Decoding A Site.
J Org Chem;
85(24): 16043-16059, 2020 12 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32902280
7.
Epidemiologic, Phenotypic, and Structural Characterization of Aminoglycoside-Resistance Gene aac(3)-IV.
Int J Mol Sci;
21(17)2020 Aug 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32854436
8.
Experimental Determination of the pKa Values of Clinically Relevant Aminoglycoside Antibiotics: Toward Establishing pKa-Activity Relationships.
ACS Omega;
9(5): 5876-5887, 2024 Feb 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38343924
9.
Phenotypic and genotypic characterization of Neisseria gonorrhoeae isolates among individuals at high risk for sexually transmitted diseases in Zurich, Switzerland.
Int J STD AIDS;
35(6): 462-470, 2024 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38297880
10.
Apramycin efficacy against carbapenem- and aminoglycoside-resistant Escherichia coli and Klebsiella pneumoniae in murine bloodstream infection models.
Int J Antimicrob Agents;
64(1): 107181, 2024 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38653351
11.
Structure-Activity Relationships for 5'' Modifications of 4,5-Aminoglycoside Antibiotics.
ChemMedChem;
17(13): e202200120, 2022 07 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35385605
12.
Apramycin susceptibility of multidrug-resistant Gram-negative blood culture isolates in five countries in Southeast Asia.
Int J Antimicrob Agents;
60(4): 106659, 2022 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35988665
13.
Synthesis and Antibacterial Activity of Propylamycin Derivatives Functionalized at the 5''- and Other Positions with a View to Overcoming Resistance Due to Aminoglycoside Modifying Enzymes.
ACS Infect Dis;
7(8): 2413-2424, 2021 08 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34114793
14.
An Advanced Apralog with Increased inâ vitro and inâ vivo Activity toward Gram-negative Pathogens and Reduced ex vivo Cochleotoxicity.
ChemMedChem;
16(2): 335-339, 2021 01 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33007139
15.
Genotypic and phenotypic analyses of aac(3) aminoglycoside-resistance gene diversity point to three distinct phenotypes of contemporary clinical relevance.
J Glob Antimicrob Resist;
29: 534-536, 2022 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34896655