Detalhe da pesquisa
1.
ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1.
Cancer Immunol Immunother;
72(12): 4145-4159, 2023 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37796298
2.
MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM.
Proc Natl Acad Sci U S A;
116(15): 7533-7542, 2019 04 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30898885
3.
Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology.
J Biol Chem;
295(52): 17935-17949, 2020 12 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32900849
4.
Expanding the Toolbox of R-Selective Amine Transaminases by Identification and Characterization of New Members.
Chembiochem;
22(7): 1232-1242, 2021 04 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33242357
5.
Current status and future opportunities for serial crystallography at MAX IV Laboratory.
J Synchrotron Radiat;
27(Pt 5): 1095-1102, 2020 Sep 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32876583
6.
Molecular Characterization of a Novel Lytic Enzyme LysC from Clostridium intestinale URNW and Its Antibacterial Activity Mediated by Positively Charged N-Terminal Extension.
Int J Mol Sci;
21(14)2020 Jul 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32664473
7.
3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-sites for High-Affinity and High-Selectivity Inhibition of Galectin-3.
Molecules;
24(24)2019 Dec 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31842451
8.
Synthesis of branched and linear 1,4-linked galactan oligosaccharides.
Org Biomol Chem;
16(7): 1157-1162, 2018 02 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29367995
9.
Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH.
J Biol Chem;
290(1): 142-56, 2015 Jan 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25371205
10.
Neutron crystallographic studies reveal hydrogen bond and water-mediated interactions between a carbohydrate-binding module and its bound carbohydrate ligand.
Biochemistry;
54(42): 6435-8, 2015 Oct 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26451738
11.
Health Care Utilization and Complications Rates among Users Of Hydrophilic-Coated Catheters.
Urol Nurs;
35(5): 239-47, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26630780
12.
Carbohydrate binding module recognition of xyloglucan defined by polar contacts with branching xyloses and CH-Π interactions.
Proteins;
82(12): 3466-75, 2014 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25302425
13.
Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer.
J Med Chem;
2024 May 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38804039
14.
Prospective de novo drug design with deep interactome learning.
Nat Commun;
15(1): 3408, 2024 Apr 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38649351
15.
Crystal structure of N-glycosylated human glypican-1 core protein: structure of two loops evolutionarily conserved in vertebrate glypican-1.
J Biol Chem;
287(17): 14040-51, 2012 Apr 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22351761
16.
Supplementation by thylakoids to a high carbohydrate meal decreases feelings of hunger, elevates CCK levels and prevents postprandial hypoglycaemia in overweight women.
Appetite;
68: 118-23, 2013 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23632035
17.
"None of us was prepared"-Caring for vulnerable people during the heatwave in Sweden in 2018.
J Emerg Manag;
21(4): 287-300, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37878400
18.
Discovery of Selective and Orally Available Galectin-1 Inhibitors.
J Med Chem;
66(24): 16980-16990, 2023 12 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38059452
19.
Minimally invasive surgery as a new clinical standard for bone anchored hearing implants-real-world data from 10 years of follow-up and 228 surgeries.
Front Surg;
10: 1209927, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37465065
20.
The Bispecific Tumor Antigen-Conditional 4-1BB x 5T4 Agonist, ALG.APV-527, Mediates Strong T-Cell Activation and Potent Antitumor Activity in Preclinical Studies.
Mol Cancer Ther;
22(1): 89-101, 2023 01 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36343381