Detalhe da pesquisa
1.
Preclinical dose response study shows NR2E3 can attenuate retinal degeneration in the retinitis pigmentosa mouse model RhoP23H+/.
Gene Ther;
31(5-6): 255-262, 2024 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38273095
2.
Nr2e3 is a genetic modifier that rescues retinal degeneration and promotes homeostasis in multiple models of retinitis pigmentosa.
Gene Ther;
28(5): 223-241, 2021 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32123325
3.
ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder.
Genet Med;
21(9): 2103-2115, 2019 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30967659
4.
The nuclear hormone receptor gene Nr2c1 (Tr2) is a critical regulator of early retina cell patterning.
Dev Biol;
429(1): 343-355, 2017 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28551284
5.
Differential dimerization of variants linked to enhanced S-cone sensitivity syndrome (ESCS) located in the NR2E3 ligand-binding domain.
Hum Mutat;
36(6): 599-610, 2015 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25703721
6.
Alzheimer's Disease: Models and Molecular Mechanisms Informing Disease and Treatments.
Bioengineering (Basel);
11(1)2024 Jan 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38247923
7.
Seeing the Future: A Review of Ocular Therapy.
Bioengineering (Basel);
11(2)2024 Feb 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38391665
8.
Corrigendum to "The Nuclear Hormone Receptor Nr2c1 (Tr2) is a critical regulator of early retina cell pattering" [Dev. Biol. 16 (2017) 30797-7].
Dev Biol;
429(1): 370, 2017 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28743516
9.
Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration.
Hum Genomics;
5(6): 538-68, 2011 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22155603
10.
Interspecies Correlations between Human and Mouse NR2E3-Associated Recessive Disease.
J Clin Med;
10(3)2021 Jan 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33513943
11.
Nr2e3-directed transcriptional regulation of genes involved in photoreceptor development and cell-type specific phototransduction.
Exp Eye Res;
89(3): 365-72, 2009 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19379737
12.
Microbiota, Microbiome, and Retinal Diseases.
Int Ophthalmol Clin;
62(2): 197-214, 2022 Apr 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35325919
13.
Focus on molecules: nuclear hormone receptor Nr2e3: impact on retinal development and disease.
Exp Eye Res;
91(2): 116-7, 2010 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20450910
14.
Role of Nuclear Receptors in Central Nervous System Development and Associated Diseases.
J Exp Neurosci;
9(Suppl 2): 93-121, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27168725
15.
Whole-Exome Sequencing in a South American Cohort Links ALDH1A3, FOXN1 and Retinoic Acid Regulation Pathways to Autism Spectrum Disorders.
PLoS One;
10(9): e0135927, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26352270
16.
Modifier genes as therapeutics: the nuclear hormone receptor Rev Erb alpha (Nr1d1) rescues Nr2e3 associated retinal disease.
PLoS One;
9(1): e87942, 2014.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24498227
17.
Characterization of a spontaneous retinal neovascular mouse model.
PLoS One;
9(9): e106507, 2014.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25188381
18.
FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression.
Invest Ophthalmol Vis Sci;
55(6): 3543-54, 2014 May 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24812550
19.
Nuclear receptor Rev-erb alpha (Nr1d1) functions in concert with Nr2e3 to regulate transcriptional networks in the retina.
PLoS One;
6(3): e17494, 2011 Mar 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21408158
20.
Genetic variations strongly influence phenotypic outcome in the mouse retina.
PLoS One;
6(7): e21858, 2011.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21779340