RESUMO
Professor A. Koneti Rao has made many critical contributions to the field of platelet research for over forty years. He joined the editorial board of Platelets as a Principal Editor in 1989 before the start of the journal and the appointment of Stan Heptinstall, who was Editor-in-Chief for 25 years. Professor Rao retired from the editorial board in 2018. This article is based on an interview with Professor Rao that took place prior to the Platelets Editorial Board meeting and lunch in 2019 during the ISTH Congress in Melbourne. Professor Rao was presented with a plaque in recognition of his service to the journal. The article is a reflection on Professor Rao's personal life and his career in science, along with his views on the past and future of Platelets. Professor Rao continues to serve as a referee for the journal.
Assuntos
Plaquetas , História do Século XXI , HumanosRESUMO
This article is taken from an interview with Professor Gustav Victor Rudolf Born (known as Gus), and focuses on his personal reflections and his distinguished career. Professor Born's innovative research led to the development of a pioneering device, the aggregometer, which opened up the field of platelet research. In this article, Professor Born gives his modest insight into the early stages of his career and the impact Hiroshima had on his decision to work on thrombosis and hemostasis. He details the key events that led to development of a machine which had a revolutionary effect on diagnosing platelet-related diseases and the development of antiplatelet agents, thereby making it a world-wide success and saving so many lives.
Assuntos
Agregação Plaquetária , História do Século XX , História do Século XXI , Humanos , Testes de Função Plaquetária/históriaRESUMO
2011 marks the 50th anniversary of the discovery of ibuprofen. This article is a focus on the personal reflections and career of Dr Stewart Adams OBE, the scientist whose research lead to the discovery of the cyclooxygenase inhibitor. When Dr Adams discovered ibuprofen, he was working as a pharmacologist in the Research Department for the Boots Pure Drug Company Ltd. Dr Adams was assigned to work on rheumatoid arthritis (RA) and chose in 1953 to search for a drug that would be effective in RA but would not be a corticosteroid. He was one of the first workers in this field that later became known as NSAIDs (Non-Steroidal Anti Inflammatory Drugs). In 1961, Dr Adams with John Nicholson, the organic chemist, filed a patent for the compound 2-(4-isobutylphenyl) propionic acid, later to become one of the most successful NSAIDs in the modern world, ibuprofen. In this article, Dr Adams gives his modest insight into the early stages and initial observations which led to this world-wide success.