Detalhe da pesquisa
1.
Safety and Pharmacokinetics of Quick-Dissolving Polymeric Vaginal Films Delivering the Antiretroviral IQP-0528 for Preexposure Prophylaxis.
Antimicrob Agents Chemother;
60(7): 4140-50, 2016 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27139475
2.
Coupled gel spreading and diffusive transport models describing microbicidal drug delivery.
Chem Eng Sci;
152: 12-20, 2016 Oct 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28042165
3.
Pharmacokinetic and Pharmacodynamic Evaluation following Vaginal Application of IQB3002, a Dual-Chamber Microbicide Gel Containing the Nonnucleoside Reverse Transcriptase Inhibitor IQP-0528 in Rhesus Macaques.
Antimicrob Agents Chemother;
60(3): 1393-400, 2015 Dec 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26666935
4.
Vaginal film drug delivery of the pyrimidinedione IQP-0528 for the prevention of HIV infection.
Pharm Res;
29(7): 1897-907, 2012 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22392331
5.
Designing Dual Compartment HIV Prevention Products: Women's Sensory Perceptions and Experiences of Suppositories for Rectal and Vaginal Use.
AIDS Res Hum Retroviruses;
38(7): 601-610, 2022 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34544269
6.
Examining the Safety, Pharmacokinetics, and Pharmacodynamics of a Rectally Administered IQP-0528 Gel for HIV Pre-Exposure Prophylaxis: A First-In-Human Study.
AIDS Res Hum Retroviruses;
37(6): 444-452, 2021 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33371779
7.
The Role of Volume in the Perceptibility of Topical Vaginal Formulations: User Sensory Perceptions and Experiences of Heterosexual Couples During Vaginal Sex.
AIDS Res Hum Retroviruses;
36(12): 1059-1070, 2020 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32988214
8.
Effects of gel volume on pharmacokinetics for vaginal and rectal applications of combination DuoGel-IQB4012, a dual chamber-dual drug HIV microbicide gel, in pigtailed macaques.
Drug Deliv Transl Res;
8(5): 1180-1190, 2018 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29761350
9.
Designing and developing suppository formulations for anti-HIV drug delivery.
Ther Deliv;
8(9): 805-817, 2017 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28825395
10.
Current Concepts for the IND-Directed Development of Microbicide Products to Prevent the Sexual Transmission of HIV.
Curr Top Med Chem;
16(10): 1118-34, 2016.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26324047
11.
Current and emerging formulation strategies for the effective transdermal delivery of HIV inhibitors.
Ther Deliv;
6(2): 217-29, 2015 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25690088
12.
The rational design and development of a dual chamber vaginal/rectal microbicide gel formulation for HIV prevention.
Antiviral Res;
120: 153-64, 2015 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26093158
13.
In vitro and ex vivo evaluations on transdermal delivery of the HIV inhibitor IQP-0410.
PLoS One;
8(9): e75306, 2013.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24058672
14.
Development of a combination microbicide gel formulation containing IQP-0528 and tenofovir for the prevention of HIV infection.
J Pharm Sci;
101(4): 1423-35, 2012 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22227864
15.
Development of topical microbicides to prevent the sexual transmission of HIV.
Antiviral Res;
85(1): 142-58, 2010 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19874851
16.
Action at a distance: lengthening adhesion bonds with poly(ethylene glycol) spacers enhances mechanically stressed affinity for improved vascular targeting of microparticles.
Langmuir;
25(17): 10038-44, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19621909
17.
Targeted delivery of PSC-RANTES for HIV-1 prevention using biodegradable nanoparticles.
Pharm Res;
26(3): 502-11, 2009 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19002569
18.
Microparticle adhesive dynamics and rolling mediated by selectin-specific antibodies under flow.
Biotechnol Bioeng;
96(3): 596-607, 2007 Feb 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16917925