Detalhe da pesquisa
1.
Seamless integration of dose-response screening and flow chemistry: efficient generation of structure-activity relationship data of ß-secretase (BACE1) inhibitors.
Angew Chem Int Ed Engl;
53(6): 1704-8, 2014 Feb 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24458566
2.
Discovery of Orally Available and Brain Penetrant AEP Inhibitors.
J Med Chem;
66(24): 17026-17043, 2023 12 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38090813
3.
Discovery of 3-Pyridyl Isoindolin-1-one Derivatives as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors.
J Med Chem;
63(13): 6876-6897, 2020 07 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32530624
4.
DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome.
ACS Chem Biol;
14(1): 37-49, 2019 01 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30452219
5.
Analysis of Current DNA Encoded Library Screening Data Indicates Higher False Negative Rates for Numerically Larger Libraries.
ACS Comb Sci;
19(4): 234-238, 2017 04 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28287689
6.
ß-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease.
J Med Chem;
56(10): 3980-95, 2013 May 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23590342
7.
SiLA: Basic standards for rapid integration in laboratory automation.
J Lab Autom;
17(2): 86-95, 2012 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22357556
8.
High-resolution capillary tube NMR. A miniaturized 5-microL high-sensitivity TXI probe for mass-limited samples, off-line LC NMR, and HT NMR.
Anal Chem;
74(17): 4464-71, 2002 Sep 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12236357