Detalhe da pesquisa
1.
Open-label phase 3 study of intravenous golimumab in patients with polyarticular juvenile idiopathic arthritis.
Rheumatology (Oxford);
60(10): 4495-4507, 2021 10 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33493312
2.
Dynamic population pharmacokinetic-pharmacodynamic modelling and simulation supports similar efficacy in glycosylated haemoglobin response with once or twice-daily dosing of canagliflozin.
Br J Clin Pharmacol;
83(5): 1072-1081, 2017 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28138980
3.
The method of averaging applied to pharmacokinetic/pharmacodynamic indirect response models.
J Pharmacokinet Pharmacodyn;
42(4): 417-26, 2015 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26142076
4.
Population pharmacokinetics and exposure-response modeling analyses of guselkumab in patients with psoriatic arthritis.
Clin Transl Sci;
15(3): 749-760, 2022 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34854241
5.
Translational PK/PD and model-informed development of JNJ-67842125, a Fab reversal agent for JNJ-64179375, a long-acting thrombin inhibitor.
Br J Pharmacol;
178(19): 3943-3958, 2021 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34008170
6.
Application of Trial Simulation in the Design of a Prospective Study for Concentration-QTc Analysis in Support of a Thorough QT Study Waiver.
AAPS J;
22(5): 101, 2020 08 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32743691
7.
Evaluating potential benefits of dose-exposure-response modeling for dose finding.
Pharm Stat;
8(3): 203-15, 2009.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19629954
8.
Trial Design and Statistical Considerations on the Assessment of Pharmacodynamic Similarity.
AAPS J;
21(3): 47, 2019 04 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30945035
9.
Utilization of Adult Data in Designing Pediatric Pharmacokinetic Studies: How Much Are Historical Adult Data Worth?
J Clin Pharmacol;
59(7): 989-996, 2019 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30748023
10.
Phase I dose-finding study of weekly single-agent patupilone in patients with advanced solid tumors.
J Clin Oncol;
23(36): 9120-9, 2005 Dec 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16301595
11.
FTY720, a novel immunomodulator in de novo kidney transplant patients: pharmacokinetics and exposure-response relationship.
J Clin Pharmacol;
45(11): 1268-78, 2005 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16239360
12.
Everolimus in de novo cardiac transplantation: pharmacokinetics, therapeutic range, and influence on cyclosporine exposure.
J Heart Lung Transplant;
22(10): 1117-25, 2003 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14550821
13.
Innovative approaches for designing and analyzing adaptive dose-ranging trials.
J Biopharm Stat;
17(6): 965-95, 2007.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18027208
14.
Pharmacokinetics of an everolimus-cyclosporine immunosuppressive regimen over the first 6 months after kidney transplantation.
Am J Transplant;
3(5): 606-13, 2003 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12752317