Detalhe da pesquisa
1.
Small molecule AX-024 reduces T cell proliferation independently of CD3ϵ/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J Biol Chem;
295(23): 7849-7864, 2020 06 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32317279
2.
The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson's disease brain as revealed by multicolor STED microscopy.
Acta Neuropathol;
142(3): 423-448, 2021 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34115198
3.
Novel ß-Glucocerebrosidase Activators That Bind to a New Pocket at a Dimer Interface and Induce Dimerization.
Angew Chem Int Ed Engl;
60(10): 5436-5442, 2021 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33238058
4.
Reply to Alarcon and Borroto: Small molecule AX-024 reduces T cell proliferation independently of CD3ε-Nck1 interaction at SH3.1.
J Biol Chem;
295(29): 10077, 2020 07 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32680972
5.
Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance.
Biochim Biophys Acta;
1848(5): 1224-33, 2015 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25725488
6.
Elucidation of direct competition and allosteric modulation of small-molecular-weight protein ligands using surface plasmon resonance methods.
J Mol Recognit;
28(8): 480-91, 2015 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25763559
7.
HLA antibody affinity determination: From HLA-specific monoclonal antibodies to donor HLA specific antibodies (DSA) in patient serum.
HLA;
102(3): 278-300, 2023 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37191252
8.
Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies.
Acta Neuropathol Commun;
10(1): 82, 2022 06 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35659116
9.
Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain.
Eur J Med Chem;
243: 114750, 2022 Dec 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36137365
10.
Rapid detection of methicillin-resistant Staphylococcus aureus (MRSA) in diverse clinical specimens by the BD GeneOhm MRSA assay and comparison with culture.
J Clin Microbiol;
48(3): 981-4, 2010 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20071545
11.
DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome.
ACS Chem Biol;
14(1): 37-49, 2019 01 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30452219
12.
Synthetic single domain antibodies for the conformational trapping of membrane proteins.
Elife;
72018 05 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29792401
13.
SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligands.
PLoS One;
12(5): e0175842, 2017.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28510609
14.
Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers.
Nat Commun;
8(1): 1476, 2017 11 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29133793
15.
Antibody-Mediated Neutralization of the Exotoxin Mycolactone, the Main Virulence Factor Produced by Mycobacterium ulcerans.
PLoS Negl Trop Dis;
10(6): e0004808, 2016 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27351976
16.
Diagnosis of whooping cough in Switzerland: differentiating Bordetella pertussis from Bordetella holmesii by polymerase chain reaction.
PLoS One;
9(2): e88936, 2014.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24586447