Detalhe da pesquisa
1.
Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion.
Hepatology;
78(5): 1418-1432, 2023 11 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36053190
2.
Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome.
Circ Res;
130(1): 80-95, 2022 01 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34809444
3.
Cargo-Specific Role for Retriever Subunit VPS26C in Hepatocyte Lipoprotein Receptor Recycling to Control Postprandial Triglyceride-Rich Lipoproteins.
Arterioscler Thromb Vasc Biol;
43(1): e29-e45, 2023 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36353989
4.
Personalised modelling of clinical heterogeneity between medium-chain acyl-CoA dehydrogenase patients.
BMC Biol;
21(1): 184, 2023 09 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37667308
5.
Selective Hepatic Cbs Knockout Aggravates Liver Damage, Endothelial Dysfunction and ROS Stress in Mice Fed a Western Diet.
Int J Mol Sci;
24(8)2023 Apr 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37108182
6.
Modeling Phenotypic Heterogeneity of Glycogen Storage Disease Type 1a Liver Disease in Mice by Somatic CRISPR/CRISPR-associated protein 9-Mediated Gene Editing.
Hepatology;
74(5): 2491-2507, 2021 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34157136
7.
Taking One Step Back in Familial Hypercholesterolemia: STAP1 Does Not Alter Plasma LDL (Low-Density Lipoprotein) Cholesterol in Mice and Humans.
Arterioscler Thromb Vasc Biol;
40(4): 973-985, 2020 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31996024
8.
A common variant in CCDC93 protects against myocardial infarction and cardiovascular mortality by regulating endosomal trafficking of low-density lipoprotein receptor.
Eur Heart J;
41(9): 1040-1053, 2020 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31630160
9.
A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice.
J Lipid Res;
61(3): 291-305, 2020 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31506275
10.
The COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR Trafficking.
Circ Res;
122(12): 1648-1660, 2018 06 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29545368
11.
FXR overexpression alters adipose tissue architecture in mice and limits its storage capacity leading to metabolic derangements.
J Lipid Res;
60(9): 1547-1561, 2019 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31253637
12.
NF-κB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFα-or diet-induced inflammation.
Biochim Biophys Acta Mol Cell Res;
1864(10): 1785-1798, 2017 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28723419
13.
Butyrate oxidation attenuates the butyrate-induced improvement of insulin sensitivity in myotubes.
Biochim Biophys Acta Mol Basis Dis;
1868(11): 166476, 2022 11 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35811030
14.
Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism.
Sci Rep;
12(1): 2512, 2022 02 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35169201
15.
The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction.
Am J Physiol Regul Integr Comp Physiol;
298(2): R275-82, 2010 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19889862
16.
Fetal liver X receptor activation acutely induces lipogenesis but does not affect plasma lipid response to a high-fat diet in adult mice.
Am J Physiol Endocrinol Metab;
297(5): E1171-8, 2009 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19724022
17.
Partial Deletion of Tie2 Affects Microvascular Endothelial Responses to Critical Illness in A Vascular Bed and Organ-Specific Way.
Shock;
51(6): 757-769, 2019 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30520765
18.
The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance.
JCI Insight;
4(11)2019 06 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31167970
19.
Corrigendum to "NF-κB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFα-or diet-induced inflammation" [Biochim. Biophys. Acta Mol. Cell Res., 1864 (2017): 1785-1798].
Biochim Biophys Acta Mol Cell Res;
1868(6): 119008, 2021 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33715857
20.
CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.
Nat Commun;
7: 10961, 2016 Mar 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26965651