Detalhe da pesquisa
1.
Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an Acute Respiratory Distress Syndrome Model.
Am J Respir Crit Care Med;
209(6): 703-715, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37972349
2.
Regulation of ingestive behaviors in the rat by GSK1521498, a novel micro-opioid receptor-selective inverse agonist.
J Pharmacol Exp Ther;
339(1): 24-34, 2011 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21712426
3.
A concise synthesis of 1,4-dihydro-[1,4]diazepine-5,7-dione, a novel 7-TM receptor ligand core structure with melanocortin receptor agonist activity.
Bioorg Med Chem;
18(5): 1822-33, 2010 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20172734
4.
Potent, selective, and orally efficacious antagonists of melanin-concentrating hormone receptor 1.
J Med Chem;
49(24): 7095-107, 2006 Nov 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17125262
5.
6-(4-chlorophenyl)-3-substituted-thieno[3,2-d]pyrimidin-4(3H)-one-based melanin-concentrating hormone receptor 1 antagonist.
J Med Chem;
49(24): 7108-18, 2006 Nov 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17125263
6.
Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules.
Br J Pharmacol;
148(5): 619-28, 2006 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16702987
7.
Characterisation of olanzapine-induced weight gain and effect of aripiprazole vs olanzapine on body weight and prolactin secretion in female rats.
Psychopharmacology (Berl);
182(2): 220-31, 2005 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16001110
8.
A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma.
Pharmacogenetics;
14(9): 627-33, 2004 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15475736
9.
Regulation of TNF-alpha secretion by a specific melanocortin-1 receptor peptide agonist.
Peptides;
24(5): 709-16, 2003 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12895657
10.
Opioid receptor modulation of hedonic taste preference and food intake: a single-dose safety, pharmacokinetic, and pharmacodynamic investigation with GSK1521498, a novel µ-opioid receptor inverse agonist.
J Clin Pharmacol;
52(4): 464-74, 2012 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21610207
11.
Lysosomes contribute to anomalous pharmacokinetic behavior of melanocortin-4 receptor agonists.
Pharm Res;
24(6): 1138-44, 2007 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17373577
12.
The discovery and optimization of pyrimidinone-containing MCH R1 antagonists.
Bioorg Med Chem Lett;
16(18): 4723-7, 2006 Sep 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16870432
13.
Novel benzimidazole-based MCH R1 antagonists.
Bioorg Med Chem Lett;
16(19): 4994-5000, 2006 Oct 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16904318
14.
Characterization of melanocortin receptors.
Curr Protoc Pharmacol;
Chapter 1: Unit1.28, 2003 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21956799
15.
Molecular identification of high and low affinity receptors for nicotinic acid.
J Biol Chem;
278(11): 9869-74, 2003 Mar 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12522134
16.
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
J Biol Chem;
278(13): 11312-9, 2003 Mar 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12496283
17.
The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids.
J Biol Chem;
278(13): 11303-11, 2003 Mar 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12496284