Detalhe da pesquisa
1.
Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer.
Cell;
175(5): 1244-1258.e26, 2018 11 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30454645
2.
Genome-wide screening and functional validation of methylation barriers near promoters.
Nucleic Acids Res;
52(9): 4857-4871, 2024 May 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38647050
3.
DNA polymerase θ protects leukemia cells from metabolically induced DNA damage.
Blood;
141(19): 2372-2389, 2023 05 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36580665
4.
TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype.
Gastroenterology;
164(6): 921-936.e1, 2023 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36764492
5.
Gestational high fat diet protects 3xTg offspring from memory impairments, synaptic dysfunction, and brain pathology.
Mol Psychiatry;
26(11): 7006-7019, 2021 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31451749
6.
Accelerated aging in normal breast tissue of women with breast cancer.
Breast Cancer Res;
23(1): 58, 2021 05 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34022936
7.
Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.
Blood;
132(1): 67-77, 2018 07 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29784639
8.
Nerve Injury-Induced Chronic Pain Is Associated with Persistent DNA Methylation Reprogramming in Dorsal Root Ganglion.
J Neurosci;
38(27): 6090-6101, 2018 07 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29875269
9.
A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer.
Nucleic Acids Res;
45(14): 8269-8281, 2017 Aug 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28531272
10.
Age-related epigenetic drift in the pathogenesis of MDS and AML.
Genome Res;
24(4): 580-91, 2014 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24414704
11.
Zebrafish embryos as a screen for DNA methylation modifications after compound exposure.
Toxicol Appl Pharmacol;
291: 84-96, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26712470
12.
TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells.
Nucleic Acids Res;
42(11): 6956-71, 2014 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24875481
13.
Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators.
Gastroenterology;
146(2): 530-38.e5, 2014 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24211491
14.
Methylation of AR locus does not always reflect X chromosome inactivation state.
Blood;
119(13): e100-9, 2012 Mar 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22286197
15.
Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation.
Nat Med;
13(1): 78-83, 2007 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17159988
16.
Association between gut microbiota and CpG island methylator phenotype in colorectal cancer.
Gut Microbes;
16(1): 2363012, 2024.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38860458
17.
Use of genome-wide DNA methylation analysis to identify prognostic CpG site markers associated with longer survival time in dogs with multicentric high-grade B-cell lymphoma.
J Vet Intern Med;
38(1): 316-325, 2024.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38115210
18.
MC180295 is a highly potent and selective CDK9 inhibitor with preclinical in vitro and in vivo efficacy in cancer.
Clin Epigenetics;
16(1): 3, 2024 01 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38172923
19.
Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer.
Genome Res;
20(10): 1369-82, 2010 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20716667
20.
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia.
Nat Genet;
32(4): 614-21, 2002 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12415268