Detalhe da pesquisa
1.
UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis.
Nature;
446(7139): 1091-5, 2007 Apr 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17410128
2.
Synthesis and characterization of [76Br]-labeled high-affinity A3 adenosine receptor ligands for positron emission tomography.
Nucl Med Biol;
36(1): 3-10, 2009 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19181263
3.
Synthesis and P2Y receptor activity of nucleoside 5'-phosphonate derivatives.
Bioorg Med Chem Lett;
19(11): 3002-5, 2009 Jun 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19419868
4.
Molecular recognition in the P2Y(14) receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucose.
Bioorg Med Chem;
17(14): 5298-311, 2009 Jul 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19502066
5.
Positive inotropic effects by uridine triphosphate (UTP) and uridine diphosphate (UDP) via P2Y2 and P2Y6 receptors on cardiomyocytes and release of UTP in man during myocardial infarction.
Circ Res;
98(7): 970-6, 2006 Apr 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16543499
6.
Synthesis and structure-activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor.
Bioorg Med Chem Lett;
18(2): 571-5, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18078749
7.
Selective A(3) adenosine receptor antagonists derived from nucleosides containing a bicyclo[3.1.0]hexane ring system.
Bioorg Med Chem;
16(18): 8546-56, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18752961
8.
Synthesis of ethyl (1S,2R,3S,4S,5S)-2,3-O-(isopropylidene)-4-hydroxy-bicyclo[3.1.0]hexane-carboxylate from L-ribose: a versatile chiral synthon for preparation of adenosine and P2 receptor ligands.
Nucleosides Nucleotides Nucleic Acids;
27(3): 279-91, 2008 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18260011
9.
P2Y1 antagonists: combining receptor-based modeling and QSAR for a quantitative prediction of the biological activity based on consensus scoring.
J Med Chem;
50(14): 3229-41, 2007 Jul 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17564423
10.
Agonists and antagonists for P2 receptors.
Novartis Found Symp;
276: 58-68; discussion 68-72, 107-12, 275-81, 2006.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16805423
11.
A3 adenosine receptors and mitogen-activated protein kinases in lung injury following in vivo reperfusion.
Crit Care;
10(2): R65, 2006.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16623960
12.
Action of nucleosides and nucleotides at 7 transmembrane-spanning receptors.
Nucleosides Nucleotides Nucleic Acids;
25(12): 1425-36, 2006.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17067963
13.
NUCLEOSIDE PRODRUGS OF A3 ADENOSINE RECEPTOR AGONISTS AND ANTAGONISTS.
Collect Czechoslov Chem Commun;
71(6): 912-928, 2006.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34815583
14.
Purine derivatives as ligands for A3 adenosine receptors.
Curr Top Med Chem;
5(13): 1275-95, 2005.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16305531
15.
(N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists.
J Med Chem;
48(6): 1745-58, 2005 Mar 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15771421
16.
Semi-rational design of (north)-methanocarba nucleosides as dual acting A(1) and A(3) adenosine receptor agonists: novel prototypes for cardioprotection.
J Med Chem;
48(26): 8103-7, 2005 Dec 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16366590
17.
Human P2Y(6) receptor: molecular modeling leads to the rational design of a novel agonist based on a unique conformational preference.
J Med Chem;
48(26): 8108-11, 2005 Dec 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16366591
18.
Role of direct RhoA-phospholipase D1 interaction in mediating adenosine-induced protection from cardiac ischemia.
FASEB J;
18(2): 406-8, 2004 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14688204
19.
Molecular recognition at purine and pyrimidine nucleotide (P2) receptors.
Curr Top Med Chem;
4(8): 805-19, 2004.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15078212
20.
Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors.
Biochem Pharmacol;
67(9): 1763-70, 2004 May 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15081875