Detalhe da pesquisa
1.
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease.
Cell;
185(26): 4937-4953.e23, 2022 12 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36563664
2.
Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy.
Nature;
572(7769): 335-340, 2019 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31316208
3.
Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice.
Proc Natl Acad Sci U S A;
119(26): e2204084119, 2022 06 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35727972
4.
Targeting mAKAPß expression as a therapeutic approach for ischemic cardiomyopathy.
Gene Ther;
30(7-8): 543-551, 2023 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35102273
5.
De novo and inherited variants in coding and regulatory regions in genetic cardiomyopathies.
Hum Genomics;
16(1): 55, 2022 11 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36357925
6.
A Novel Recessive Mutation in SPEG Causes Early Onset Dilated Cardiomyopathy.
PLoS Genet;
16(9): e1009000, 2020 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32925938
7.
Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy.
Eur Heart J;
43(36): 3477-3489, 2022 09 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35728000
8.
Unfolded Protein Response as a Compensatory Mechanism and Potential Therapeutic Target in PLN R14del Cardiomyopathy.
Circulation;
144(5): 382-392, 2021 08 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33928785
9.
Insulin Growth Factor Phenotypes in Heart Failure With Preserved Ejection Fraction, an INSPIRE Registry and CATHGEN Study.
J Card Fail;
28(6): 935-946, 2022 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34979242
10.
The potential of CRISPR-Cas9 prime editing for cardiovascular disease research and therapy.
Curr Opin Cardiol;
37(5): 413-418, 2022 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35880456
11.
Telomere shortening is a hallmark of genetic cardiomyopathies.
Proc Natl Acad Sci U S A;
115(37): 9276-9281, 2018 09 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30150400
12.
A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay.
Circulation;
139(6): 799-811, 2019 02 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30586709
13.
Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs.
Proc Natl Acad Sci U S A;
114(52): E11111-E11120, 2017 12 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29203658
14.
Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling.
Stem Cells;
36(2): 265-277, 2018 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29086457
15.
A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases.
Circ Res;
120(10): 1561-1571, 2017 May 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28246128
16.
Concise Review: Mending a Broken Heart: The Evolution of Biological Therapeutics.
Stem Cells;
35(5): 1131-1140, 2017 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28233392
17.
Recent Progress in Genome Editing Approaches for Inherited Cardiovascular Diseases.
Curr Cardiol Rep;
20(7): 58, 2018 06 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29860642
18.
Human induced pluripotent stem cell-derived cardiomyocytes: insights into molecular, cellular, and functional phenotypes.
Circ Res;
117(1): 80-8, 2015 Jun 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26089365
19.
A Rapid, High-Quality, Cost-Effective, Comprehensive and Expandable Targeted Next-Generation Sequencing Assay for Inherited Heart Diseases.
Circ Res;
117(7): 603-11, 2015 Sep 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26265630
20.
Genomic correction of familial cardiomyopathy in human engineered cardiac tissues.
Eur Heart J;
37(43): 3282-3284, 2016 Nov 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27450564