Detalhe da pesquisa
1.
Late-stage optimization of a tercyclic class of S1P3-sparing, S1P1 receptor agonists.
Bioorg Med Chem Lett;
26(2): 466-471, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26687487
2.
Extending (Q)SARs to incorporate proprietary knowledge for regulatory purposes: A case study using aromatic amine mutagenicity.
Regul Toxicol Pharmacol;
77: 1-12, 2016 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26879463
3.
Discovery of MK-4688: an Efficient Inhibitor of the HDM2-p53 Protein-Protein Interaction.
J Med Chem;
64(21): 16213-16241, 2021 11 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34714078
4.
An in silico method for predicting Ames activities of primary aromatic amines by calculating the stabilities of nitrenium ions.
J Chem Inf Model;
50(2): 274-97, 2010 Feb 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20078034
5.
Evaluation of respiratory parameters in rats and rabbits exposed to methyl iodide.
Inhal Toxicol;
21(6): 505-11, 2009 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19519150
6.
Two-day inhalation toxicity study of methyl iodide in the rat.
Inhal Toxicol;
21(6): 480-7, 2009 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19519148
7.
Absorption, distribution, metabolism, and elimination of 8-2 fluorotelomer alcohol in the rat.
Toxicol Sci;
91(2): 341-55, 2006 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16543293
8.
Genetic toxicology in the 21st century: reflections and future directions.
Environ Mol Mutagen;
52(5): 339-54, 2011 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21538556
9.
Comparative metabolism of geranyl nitrile and citronellyl nitrile in mouse, rat, and human hepatocytes.
Drug Metab Dispos;
34(6): 1019-29, 2006 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16540590
10.
In vitro studies in microsomes from rat and human liver, kidney, and intestine suggest that perfluorooctanoic acid is not a substrate for microsomal UDP-glucuronosyltransferases.
Drug Chem Toxicol;
28(3): 281-7, 2005.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16051554
11.
Subcellular distribution and protein binding of perfluorooctanoic acid in rat liver and kidney.
Drug Chem Toxicol;
28(2): 197-209, 2005.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15865261
12.
Binding of perfluorooctanoic acid to rat and human plasma proteins.
Chem Res Toxicol;
16(6): 775-81, 2003 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12807361