Detalhe da pesquisa
1.
Nanoliposome C6-Ceramide in combination with anti-CTLA4 antibody improves anti-tumor immunity in hepatocellular cancer.
FASEB J;
36(4): e22250, 2022 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35294071
2.
Alterations in sphingolipid composition and mitochondrial bioenergetics represent synergistic therapeutic vulnerabilities linked to multidrug resistance in leukemia.
FASEB J;
36(1): e22094, 2022 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34888943
3.
Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia.
FASEB J;
36(10): e22514, 2022 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36106439
4.
Nervonic acid limits weight gain in a mouse model of diet-induced obesity.
FASEB J;
34(11): 15314-15326, 2020 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32959931
5.
Glucosylceramide production maintains colon integrity in response to Bacteroides fragilis toxin-induced colon epithelial cell signaling.
FASEB J;
34(12): 15922-15945, 2020 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33047400
6.
Glucosylceramidase Maintains Influenza Virus Infection by Regulating Endocytosis.
J Virol;
93(12)2019 06 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30918081
7.
Pivotal role of mitophagy in response of acute myelogenous leukemia to a ceramide-tamoxifen-containing drug regimen.
Exp Cell Res;
381(2): 256-264, 2019 08 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31112736
8.
Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells.
J Lipid Res;
60(9): 1590-1602, 2019 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31363040
9.
Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation.
J Lipid Res;
60(6): 1078-1086, 2019 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30962310
10.
Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice.
Gastroenterology;
154(4): 1024-1036.e9, 2018 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29408569
11.
Conductance-Based Biophysical Distinction and Microfluidic Enrichment of Nanovesicles Derived from Pancreatic Tumor Cells of Varying Invasiveness.
Anal Chem;
91(16): 10424-10431, 2019 08 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31333013
12.
Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection.
J Immunol;
199(2): 677-687, 2017 07 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28600291
13.
Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo.
Mol Pharm;
15(3): 721-728, 2018 03 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28901776
14.
Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model.
J Hepatol;
66(1): 75-85, 2017 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27520877
15.
Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer.
Nanomedicine;
13(7): 2313-2324, 2017 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28673852
16.
Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia.
J Lipid Res;
57(7): 1231-42, 2016 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27140664
17.
Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished extravasation in metastatic carcinoma cells.
J Biol Chem;
290(13): 8632-43, 2015 Mar 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25681441
18.
Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics.
Biochim Biophys Acta;
1851(7): 919-28, 2015 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25769964
19.
Formation and role of exosomes in cancer.
Cell Mol Life Sci;
72(4): 659-71, 2015 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25336151
20.
The apoptotic mechanism of action of the sphingosine kinase 1 selective inhibitor SKI-178 in human acute myeloid leukemia cell lines.
J Pharmacol Exp Ther;
352(3): 494-508, 2015 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25563902