Detalhe da pesquisa
1.
Quantification of Phosphonate Drugs by 1H-31P HSQC Shows That Rats Are Better Models of Primate Drug Exposure than Mice.
Anal Chem;
94(28): 10045-10053, 2022 07 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35792073
2.
Anaplerotic nutrient stress drives synergy of angiogenesis inhibitors with therapeutics targeting tumor metabolism.
bioRxiv;
2023 Oct 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37214825
3.
Generation and Validation of an Anti-Human PANK3 Mouse Monoclonal Antibody.
Biomolecules;
12(9)2022 09 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36139163
4.
Prodrugs of a 1-Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of ENO1-Deleted Cancers.
J Med Chem;
65(20): 13813-13832, 2022 10 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36251833
5.
Impaired anaplerosis is a major contributor to glycolysis inhibitor toxicity in glioma.
Cancer Metab;
9(1): 27, 2021 Jun 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34172075
6.
Pharmacokinetics of Orally Administered GS-441524 in Dogs.
bioRxiv;
2021 May 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34100016
7.
Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine.
Nat Commun;
12(1): 4228, 2021 07 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34244484
8.
Robust detection of oncometabolic aberrations by 1H-13C heteronuclear single quantum correlation in intact biological specimens.
Commun Biol;
3(1): 328, 2020 06 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32587392
9.
Bioreducible Phosphonoamidate Pro-drug Inhibitor of Enolase: Proof of Concept Study.
ACS Med Chem Lett;
11(7): 1484-1489, 2020 Jul 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32676158
10.
An enolase inhibitor for the targeted treatment of ENO1-deleted cancers.
Nat Metab;
2(12): 1413-1426, 2020 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33230295
11.
An In Vivo Screen Identifies PYGO2 as a Driver for Metastatic Prostate Cancer.
Cancer Res;
78(14): 3823-3833, 2018 07 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29769196
12.
Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression.
Cancer Discov;
6(1): 80-95, 2016 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26701088
13.
Author Correction: An enolase inhibitor for the targeted treatment of ENO1-deleted cancers.
Nat Metab;
3(1): 122, 2021 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33340032