Detalhe da pesquisa
1.
Identification and characterization of second-generation EZH2 inhibitors with extended residence times and improved biological activity.
J Biol Chem;
296: 100349, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33524394
2.
Structural and functional analysis of two di-domain aromatase/cyclases from type II polyketide synthases.
Proc Natl Acad Sci U S A;
112(50): E6844-51, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26631750
3.
Substituted diphenyl ethers as a novel chemotherapeutic platform against Burkholderia pseudomallei.
Antimicrob Agents Chemother;
58(3): 1646-51, 2014.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24379198
4.
Comprehensive Target Engagement by the EZH2 Inhibitor Tulmimetostat Allows for Targeting of ARID1A Mutant Cancers.
Cancer Res;
2024 Jun 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38833522
5.
Rational optimization of drug-target residence time: insights from inhibitor binding to the Staphylococcus aureus FabI enzyme-product complex.
Biochemistry;
52(24): 4217-28, 2013 Jun 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23697754
6.
Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time.
ACS Med Chem Lett;
11(6): 1205-1212, 2020 Jun 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32551002
7.
Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhibitors.
ACS Med Chem Lett;
11(6): 1213-1220, 2020 Jun 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32551003
8.
An unusual case of shunting across the atrial septum after mitral valve repair.
J Am Soc Echocardiogr;
18(1): 78-9, 2005 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15637495
9.
Low rates of exercise in patients with metabolic syndrome after an acute coronary syndrome.
Clin Cardiol;
28(11): 530-3, 2005 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16450797
10.
Malignant hypertension presenting as hemolysis, thrombocytopenia, and renal failure.
Rev Cardiovasc Med;
4(4): 255-9, 2003.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14674379
11.
Pd-catalyzed bis-cyclization/dimerization reactions of ω-aminovinyl halides.
Org Lett;
15(14): 3694-7, 2013 Jul 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23815282
12.
Palladium-catalyzed Catellani aminocyclopropanation reactions with vinyl halides.
Org Lett;
15(12): 3158-61, 2013 Jun 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23746296
13.
Carbenylative amination with N-tosylhydrazones.
Org Lett;
14(12): 3233-5, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22642752