Detalhe da pesquisa
1.
Optimizing tuberculosis treatment efficacy: Comparing the standard regimen with Moxifloxacin-containing regimens.
PLoS Comput Biol;
19(6): e1010823, 2023 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37319311
2.
A virtual host model of Mycobacterium tuberculosis infection identifies early immune events as predictive of infection outcomes.
J Theor Biol;
539: 111042, 2022 04 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35114195
3.
IL-10 Impairs Local Immune Response in Lung Granulomas and Lymph Nodes during Early Mycobacterium tuberculosis Infection.
J Immunol;
204(3): 644-659, 2020 02 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31862711
4.
Dynamic balance of pro- and anti-inflammatory signals controls disease and limits pathology.
Immunol Rev;
285(1): 147-167, 2018 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30129209
5.
Systems biology predicts that fibrosis in tuberculous granulomas may arise through macrophage-to-myofibroblast transformation.
PLoS Comput Biol;
16(12): e1008520, 2020 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33370784
6.
A computational model tracks whole-lung Mycobacterium tuberculosis infection and predicts factors that inhibit dissemination.
PLoS Comput Biol;
16(5): e1007280, 2020 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32433646
7.
A Framework for Network-Based Epidemiological Modeling of Tuberculosis Dynamics Using Synthetic Datasets.
Bull Math Biol;
82(6): 78, 2020 06 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32535697
8.
Evaluating vaccination strategies for tuberculosis in endemic and non-endemic settings.
J Theor Biol;
469: 1-11, 2019 05 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30851550
9.
Dose finding for new vaccines: The role for immunostimulation/immunodynamic modelling.
J Theor Biol;
465: 51-55, 2019 03 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30639297
10.
Low Levels of T Cell Exhaustion in Tuberculous Lung Granulomas.
Infect Immun;
86(9)2018 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29891540
11.
Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach.
PLoS Comput Biol;
13(8): e1005650, 2017 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28817561
12.
Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization.
PLoS Pathog;
11(1): e1004603, 2015 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25611466
13.
Identifying mechanisms driving formation of granuloma-associated fibrosis during Mycobacterium tuberculosis infection.
J Theor Biol;
429: 1-17, 2017 09 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28642013
14.
Computational and Empirical Studies Predict Mycobacterium tuberculosis-Specific T Cells as a Biomarker for Infection Outcome.
PLoS Comput Biol;
12(4): e1004804, 2016 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27065304
15.
Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity-mediated antimicrobial responses with caseation during mycobacterium tuberculosis infection.
J Immunol;
194(2): 664-77, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25512604
16.
Multiscale Model of Mycobacterium tuberculosis Infection Maps Metabolite and Gene Perturbations to Granuloma Sterilization Predictions.
Infect Immun;
84(5): 1650-1669, 2016 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26975995
17.
Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection.
Infect Immun;
83(1): 324-38, 2015 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25368116
18.
Intracellular bacillary burden reflects a burst size for Mycobacterium tuberculosis in vivo.
PLoS Pathog;
9(2): e1003190, 2013 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23436998
19.
Effectiveness of contact investigations for tuberculosis control in Arkansas.
J Theor Biol;
380: 238-46, 2015 Sep 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26051196
20.
A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment.
J Theor Biol;
367: 166-179, 2015 Feb 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25497475